Epistemis

H&E · Endocrine · open case 01

Pathological anatomy · Endocrine

Tumour biopsy showing poorly differentiated cells with scarce cytoplasm and vesicular nuclei with inconspicuous nucleoli. High mitotic index and apoptotic figures were present. Immunohistochemical reactions were positive for cytokeratin 8 and 20 and neuroendocrine markers (chromogranin, synaptophysin and CD56/NCAM); TTF-1 was not expressed (H&E stain, 40x).
Tumour biopsy showing poorly differentiated cells with scarce cytoplasm and vesicular nuclei with inconspicuous nucleoli. High mitotic index and apoptotic figures were present.…

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Category
Endocrine
Difficulty
advanced
Type
Clinical microscopy
Mode
H&E
Stain
H&E

Origin: MultiCaRe · figure from open-access article PMC3814281 · License CC BY

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