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H&E · Skin · open case 02

Pathological anatomy · Skin

(A, B). High power The biopsy specimen showed marked proliferation of irregular sebaceous lobules of different sizes and shapes in the dermis. The cells of the lobules are mostly undifferentiated and demonstrated marked cylologic atypia with considerable nuclear pleomorphism and few mitotic activities. Some of the sebaceous lobules showed areas composed of atypical keratinizing cells. The overlying epidermis is normal with marked dermal fibrosis. Immunoperoxidase staining showed positive reaction for cytokeratin (CK), focal positive for epithelial membrane antigen (EMA) and negative reaction for carcino-embryonic antigen (CEA).
(A, B). High power The biopsy specimen showed marked proliferation of irregular sebaceous lobules of different sizes and shapes in the dermis. The cells of the lobules are mostly…

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PreviousImmunostaining · Digestive system · open case 03
Category
Skin
Difficulty
advanced
Type
Clinical microscopy
Mode
H&E
Stain
H&E

Origin: MultiCaRe · figure from open-access article PMC3161692 · License CC BY

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