Epistemis

APACHE II (Acute Physiology and Chronic Health Evaluation II)

Severity score for the first 24 h of ICU admission: twelve acute physiology variables (APS) plus points for age and chronic health. Range 0–71. It is calculated with the most deranged values from those 24 hours.

Required inputs

The inputs this calculator asks for inside the app.
VariableExample value
Core temperature (°C)—
Mean arterial pressure (mmHg)—
Heart rate (bpm)—
Respiratory rate (bpm)—
FiO2 (fraction, 0.21–1.0)—
PaO2 (mmHg) — used if FiO2 < 0.5—
A-aDO2 gradient (mmHg) — used if FiO2 >= 0.5—
arterial pH—
Serum sodium (mmol/L)—
Serum potassium (mmol/L)—
Serum creatinine (mg/dL)—
Acute kidney failure? (doubles the creatinine points)—
Hematocrit (%)—
White blood cells (x10^3/mm3)—
Glasgow Coma Scale (3–15)—
Age (years)—
Severe chronic disease or immunosuppression—

Run the calculation in the app

This page explains the score but does not run it. In Epistemis, the calculator validates units, flags values outside physiological ranges, and provides the interpretation that a number alone cannot convey.

Epistemis is educational review material. It is not a medical device, does not diagnose or prescribe treatment, and does not replace formal medical training, current clinical guidelines, or professional clinical judgment.

Specialty
Intensive Care
Area
Specialties
Variable phases
17
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