Advanced Allergology: Hymenoptera Venom Allergy and Anaphylaxis — Scientific-Academic Guide

Allergology and Immunology · Clinical Specialties

How it begins

A comprehensive and in-depth analysis of proteomics, the immunopathology of mast cell and basophil degranulation, global precision diagnostic guidelines, and contemporary therapeutic algorithms for immunotherapy and anaphylactic shock.

What it covers

1. Hymenoptera Allergy and Anaphylaxis
2. Taxonomy and Biology of Hymenoptera
3. · Families and Species of Allergological Importance
4. Venom Proteomics and Biochemistry
5. · Major and Minor Allergens of Apis mellifera and Vespidae
6. Immunopathology of IgE-Mediated Allergy
7. · The Immune Sensitization Phase
8. · Effector Phase: Intracellular Signaling and Degranulation
9. · Preformed and De Novo Synthesis Mediators
10. Epidemiology, Risk Factors and Associated Comorbidities
11. · Severity and Lethality Risk Factors
12. Clinical Classification of Reactions by Hymenoptera
13. · 1. Local Reactions and Large Local Reactions (LLRs)
14. · 2. Systemic Allergic Reactions: Severity Scales
15. Multisystemic Pathophysiology of Anaphylaxis
16. · Mechanics of Hemodynamic Collapse: Distributive and Cardiogenic Shock
17. Precision Diagnosis of Poison Allergy
18. · 1. Skin Tests: Prick Test and Intradermorreaction (ID)
19. · 2. Precision In Vitro Diagnostics: Component-Resolved Diagnostics (CRD)
20. The Basophil Activation Test (BAT)
21. · Cytometric Fundamentals of Activation
22. · Specific Clinical Indications of BAT
23. Treatment of Acute Anaphylaxis
24. · Multireceptor Pharmacodynamic Mechanism of Adrenaline
25. Management of Refractory Anaphylaxis and Critical Support
26. · Critical Support and Hemodynamic Resuscitation Algorithm
27. · Advanced Airway Control under Laryngeal Angioedema
28. Immunotherapy with Hymenoptera Venom (VIT): Selection Criteria
29. · Indications for VIT according to Severity and Immunology
30. · Contraindications of Immunotherapy
31. VIT Induction Protocols
32. · VIT Induction Schemes
33. Maintenance, Effectiveness Monitoring and Termination of VIT
34. · Guidelines for Extending Maintenance Intervals
35. · Criteria for Cessation of VIT after 5 Years
36. Prescription of Adrenaline Autoinjectors and Emergency Plans
37. · Double Prescription Criteria for Autoinjectors (Two Devices)