Allergology — Allergic Cutaneous Pathology

Allergology and Immunology · Clinical Specialties

How it begins

Immunocutaneous physiology, atopic dermatitis, urticaria, angioedema, contact dermatitis, serious adverse drug reactions (SCARs), cutaneous autoinflammatory syndromes, biomarkers and latest generation therapeutics.

What it covers

1. Immunophysiology of the Skin Barrier
2. · Structural and Molecular Components of the Barrier
3. · Epithelial Maturation and Keratinic Dynamics
4. · Epidermal Immunology and Alarm Cascades (Alarminas)
5. Atopic Dermatitis: Immunopathology and Phenotypes
6. · The Dual Hypothesis: "Inside-Out" vs "Outside-In"
7. · Immunological Phases of Atopic Dermatitis
8. · Cytokine Signaling Pathways in AD
9. · Clinical Endotypes and Phenotypes
10. · Grading and Severity Systems of Atopic Dermatitis
11. Urticaria and Angioedema: Mast Cell Physiopathology
12. · Mast Cell Activation Mechanisms
13. · Physiology of the Mast Cell Mediator
14. Diagnosis and Management Algorithms
15. · Activity Recording Systems: UAS7
16. · Therapeutic Algorithm for Chronic Urticaria (Global Consensus)
17. Hereditary Angioedema: C1-Inhibitor Deficiency
18. · Pathophysiology of the Contact System (Callicrein-Kinin)
19. · Phenotypic and Genotypic Classification of HAE
20. · Specific Therapeutic Management
21. Allergic Contact Dermatitis (ACD)
22. · Pathophysiology of Haptenization and Antigenic Presentation
23. Common Allergens and Patch Tests
24. · Analysis of Prevalent Contact Allergens
25. · Clinical Application and Reading Protocol (TRUE Test / GEIDAC)
26. · International Morphological Grading (ICDRG Criteria)
27. Contact Dermatitis: Allergic vs Irritative
28. Serious Adverse Skin Drug Reactions (SCARs)
29. · Diagnostic and Severity Profiles in SCARs
30. · Detailed Molecular Physiopathology
31. · Precision Pharmacogenetic Associations (HLA Haplotypes)
32. Professional and Occupational Dermatoses
33. · Allergy to Natural Rubber Latex (NRL)
34. Immune Dysregulation and Autoinflammatory Syndromes
35. · Cryopyrin Associated Periodic Syndromes (CAPS)
36. · Neutrophilic Urticarial Dermatoses (NUD)
37. In Vivo and In Vitro Diagnostic Tests
38. · Epicutaneous Puncture Tests (Prick Test) and Intradermorreaction
39. · Molecular Component Diagnosis (CRD)
40. · Basophil Activation Test (TAB / BAT)
41. New Therapeutic Targets and Precision Medicine
42. · Arsenal of Next Generation Monoclonal (Biological) Antibodies
43. · Janus Kinase Inhibitors (JAK Inhibitors / Oral Small Molecules)
44. Skin-Systemic Emergencies: Anaphylaxis
45. · Universal Clinical Diagnostic Criteria (WAO / EAACI)
46. · Immediate Emergency Action Protocol
47. · Second Line Treatments (Should never delay Adrenaline)