Antifungals: Mechanisms of Action, Pharmacology, and Resistance — Medical Microbiology

Microbiology · Basic Sciences

How it begins

Polienos (anfotericina B desoxicolato vs liposomal), azoles y citocromo P450, equinocandinas fungicidas, flucitosina, terbinafina y resistencia FKS.

What it covers

1. 1. Polyenes: Amphotericin B Deoxycholate vs Liposomal, and Nystatin
2. 2. Azoles: fluconazole, itraconazole, voriconazole, posaconazole, and isavuconazole
3. · Systematic Comparison of the Clinically Used Triazoles
4. 3. Echinocandins: Caspofungin, Micafungin and Anidulafungin
5. 4. Flucytosine and Terbinafine
6. 5. Molecular Mechanisms of Fungal Resistance to Antifungals
7. 6. Antiviral and Antifungal Resistance: Mechanisms and the Emergence of Candida auris
8. 7. Map of Antifungal Targets
9. 8. New and Investigational Antifungals
10. 9. Practical Use: Levels, Interactions and Azole Resistance
11. 10. Reasoned Clinical Cases
12. 11. Common Mistakes and Exam Pearls
13. 12. References and Sources for Further Reading