Integrating Pathology Block — Immunopathology · Aging · Microbiota · Environmental · Neurodegeneration · Iatrogenics

General Pathology · Basic Sciences

How it begins

Comprehensive and exhaustive analysis of immunopathology, aging, microbiota, environmental pathology, bases of neurodegeneration and iatrogenesis, with emphasis on molecular mechanisms, pathophysiology and clinical correlations.

What it covers

1. Six Modules of General Pathology
2. Immunopathology
3. · Basics: Inflammation and its 5 R's
4. · Immunological Tolerance
5. · Type I Hypersensitivity — Anaphylactic / Immediate (IgE)
6. · Type II Hypersensitivity — Antibody-Mediated (IgG/IgM)
7. · Type III Hypersensitivity — Mediated by Immune Complexes (IC)
8. · Type IV Hypersensitivity — Delayed / T Lymphocyte Mediated
9. · Autoimmunity: Mechanisms and Theories
10. · Systemic Autoimmune Diseases
11. · Immunodeficiencies
12. Biology of Aging
13. · Primary Characteristics — Telomeric Attrition
14. · Theories of Aging
15. · Antagonistic Characteristics — Cellular Senescence
16. · Inflammaging and IL-11
17. · Genetic Determination: Progeroid Syndromes
18. · Physiological and Pathological Changes by System
19. Intestinal Microbiota and its Role in Health
20. · Intestine-Vascular Barrier: The Three Layers of Defense
21. · Composition of the Intestinal Microbiota
22. · Functions of the Microbiota
23. · Short Chain Fatty Acids (SCFAs) — Microbial Messengers
24. · Dysbiosis and Leaky Gut Syndrome
25. · Microbiota-Gut-Brain Axis
26. Environmental Pathology
27. · Greenhouse Effect and Climate Change
28. · Smoking — The Main Preventable Toxin
29. · Air Pollution and Pulmonary Reaction
30. · Toxic and Carcinogenic Metals
31. · Non-Therapeutic Agents
32. · Ultraviolet Radiation
33. Bases of Neurodegeneration
34. · General Physiopathological Hypotheses
35. · Alzheimer's disease (AD)
36. · Parkinson's disease (PD)
37. Iatrogenesis and Patient Safety
38. · Classification of Iatrogenesis
39. · Causes of Iatrogenesis
40. · Related Terminology: Bad Praxis
41. · Iatrogenicity in the Medical Interview
42. · Iatrogenicity in the Use of Information
43. · Patient Safety and Prevention