Epistemis

High Precision Clinical Calculators: Intensive Care and Critical Medicine

Intensive Medicine · Clinical Specialties

How it begins

A comprehensive and rigorous compendium of mathematical tools and decision algorithms based on physiology and clinical evidence for the management of patients with hemodynamic instability, severe respiratory failure, and multiple organ dysfunction.

What it covers

  1. Hemodynamics and Tissue Perfusion in the Critical Patient
  2. · 01. Cardiac Output by Fick's Principle and Vascular Resistance
  3. · 02. Cerebral Perfusion Pressure (CPP) and Intracranial Compliance
  4. · 03. Shock and Inotropic Load Indices
  5. Mechanical Ventilation and Arterial Gases in the ICU
  6. · 04. Alveolar-Arterial Oxygen Gradient ($A\text{-}a\text{ Gradient}$) and Kirby Index
  7. · 05. Predictive Tidal Volume (ARDSNet Protocol)
  8. · 06. ROX Index for High Flow Nasal Cannula
  9. Complex Acid-Base Balance in Critical Care Medicine
  10. · 07. Anion Gap Corrected by Albumin and Delta-Delta ($\Delta / \Delta$)
  11. · 08. Stewart Physicochemical Method (SID, SIG)
  12. Physiological Scoring and Severity Systems
  13. · 09. Extended Glasgow Coma Scale with Pupillary Reactivity (GCS-P)
  14. · 10. SOFA (Sequential Organ Failure Assessment) Score Calculator
  15. · 11. Rapid Sepsis Screening: qSOFA vs. SIRS criteria
  16. Critical Nephrology, Fluids and Resuscitation in Burns
  17. · 12. Calculation of Free Water Deficit in Hypernatremia
  18. · 13. Dynamic Glomerular Filtration Rate (Modified Jelliffe Equation)
  19. · 14. Parkland Formula for Fluid Resuscitation in Large Burns
  20. Critical Pharmacology and Infusion Pumps
  21. · 15. Vasoactive Dosage Converter and Calculator (mcg/kg/min to mL/h)
  22. · 16. Infusion of Sedatives and Anesthetics (Propofol / Dexmedetomidine)
  23. Advanced Clinical Simulator: ICU QBank

The complete study guide is in the app

This page summarizes the outline. The full interactive study guide —with high-yield diagrams, clinical tables, and board review cases— can be read inside Epistemis, completely offline and ad-free.

Subject
Intensive Medicine
Category
Clinical Specialties
Type
Study Guide
Sections
23
Reviewed
2026-09-05
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