Epistemis

Rheumatological Compendium · Internal Medicine

Internal Medicine · Clinical Specialties

How it begins

Fibromyalgia (FM) is a chronic widespread pain syndrome characterized by diffuse musculoskeletal pain, chronic fatigue, sleep disturbances, and a variable set of somatic and cognitive symptoms, in the absence of demonstrable inflammation or structural tissue damage. It constitutes the paradigm of central sensitization syndromes and represents the second most frequent cause of rheumatological consultation...

What it covers

  1. · Rheumatological Compendium
  2. Fibromyalgia
  3. · Pathophysiology — Central Sensitization
  4. · Clinical Manifestations
  5. · ACR Diagnostic Criteria 2010/2016
  6. · Differential Diagnosis
  7. · Treatment — Mandatory Multimodal Approach
  8. Sjögren's syndrome
  9. · Pathogenesis — Gene-Environment-Immunity Interaction
  10. · Glandular Clinical Manifestations
  11. · ACR/EULAR Classification Criteria 2016
  12. · Extraglandular Manifestations — The Systemic SS
  13. · Lymphoma Risk — The Most Serious Complication
  14. · Treatment
  15. Antiphospholipid syndrome
  16. · Pathogenic Mechanisms — Autoimmune Thrombosis
  17. · Clinical Manifestations
  18. · Classification Criteria — Revised Sapporo (Sydney 2006) and Proposed ACR/EULAR 2023
  19. · Laboratory — Antiphospholipid Antibody Profile
  20. · Catastrophic APS (CAPS) — Rheumatological Emergency
  21. · Anticoagulant Treatment — Strategies according to the Profile
  22. Relapsing Polychondritis
  23. · Pathogenesis
  24. · Clinical Manifestations — Cartilaginous and Systemic Involvement
  25. · Diagnostic Criteria
  26. · Airway Commitment — Vital Urgency
  27. · Treatment

The complete study guide is in the app

This page summarizes the outline. The full interactive study guide —with high-yield diagrams, clinical tables, and board review cases— can be read inside Epistemis, completely offline and ad-free.

Subject
Internal Medicine
Category
Clinical Specialties
Type
Study Guide
Sections
27
Reviewed
2026-08-02
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