Epistemis

Diseases of the Stomach and Duodenum · Internal Medicine

Internal Medicine · Clinical Specialties

How it begins

A comprehensive guide to pathophysiology, semiology, diagnosis and management of gastroduodenal pathologies, with emphasis on clinical integration and internist reasoning.

What it covers

  1. Anatomophysiological foundations of the stomach and duodenum
  2. · Anatomical organization and functional regions
  3. · Regulation of acid secretion
  4. · The mucosal barrier: the three lines of defense
  5. Clinical approach: dyspepsia, warning signs and diagnostic strategy
  6. · Semiology of epigastric pain oriented to etiology
  7. · Algorithm for management of uninvestigated dyspepsia
  8. Gastritis and gastropathies
  9. · Acute gastritis
  10. · Chronic gastritis: the three major forms
  11. · Special forms of gastritis
  12. · Gastropathies (without significant inflammation)
  13. Helicobacter pylori
  14. · Survival and pathogenesis strategies
  15. · Diagnostic methods
  16. · Eradication indications
  17. · Eradication schemes
  18. Peptic ulcer disease
  19. · Etiology
  20. · Gastric vs duodenal ulcer: the key comparison
  21. · Clinical manifestations
  22. · Diagnosis
  23. · Treatment
  24. Gastropathy and ulcer due to NSAIDs
  25. · Risk factors for gastrointestinal complications
  26. · Prevention (gastroprotection)
  27. Zollinger-Ellison syndrome and hypersecretory states
  28. · Clinical manifestations
  29. · Diagnosis
  30. · Treatment
  31. Functional dyspepsia
  32. · Pathophysiology (multifactorial disorder)
  33. · Stepped management
  34. Motor disorders: gastroparesis and related syndromes
  35. · Etiology
  36. · Treatment
  37. Premalignant lesions and gastric polyps
  38. · Risk staging: OLGA and OLGIM
  39. · Gastric polyps
  40. Gastric adenocarcinoma
  41. · Laurén classification: the two diseases
  42. · Risk factors
  43. · Clinical manifestations and signs at a distance
  44. · Diagnosis and staging
  45. · Treatment principles
  46. MALT lymphoma, GIST and gastric neuroendocrine tumors
  47. · Gastric MALT lymphoma
  48. · Gastrointestinal stromal tumor (GIST)
  49. · Gastric neuroendocrine tumors (carcinoids)
  50. Complications: hemorrhage, perforation and obstruction
  51. · Upper gastrointestinal bleeding (UGIB)
  52. · Perforation
  53. · Obstruction (pyloric/gastric outlet stenosis)
  54. Special entities
  55. Integrative synthesis
  56. · The four axes that organize pathology
  57. · Golden rules for practice

The complete study guide is in the app

This page summarizes the outline. The full interactive study guide —with high-yield diagrams, clinical tables, and board review cases— can be read inside Epistemis, completely offline and ad-free.

Subject
Internal Medicine
Category
Clinical Specialties
Type
Study Guide
Sections
57
Reviewed
2026-08-02
Download Epistemis