Epidemiology of Non-Communicable Diseases (NCDs) and Prevention — Treatise on Preventive Medicine and Public Health

Public Health and Epidemiology · Clinical Bases

How it begins

A comprehensive, master's-level compendium on the dynamics of NCDs: from demographic transition and epigenetic mechanisms of fetal health, to mathematical models of causal inference, the design of highly effective public health policies, and Geoffrey Rose's prevention paradox.

What it covers

1. NCD Epidemiology and Prevention
2. Epidemiological Transition and Global Burden of NCDs
3. · Global Burden of Disease (GBD) Metrics
4. Social Determinants and Genetic-Environmental Interactions
5. · Epigenetic Mechanisms of Fetal Programming
6. · Social Determinants of Health (SDH) and the Health Gradient
7. Systemic Pathophysiology of Metabolic Risk Factors
8. · The NLRP3 Inflammasome and the Inflammatory Cascade
9. · Endothelial Dysfunction and eNOS Uncoupling
10. · Insulin Resistance: Blockage of the PI3K Pathway
11. Cardiovascular Epidemiology (CVD)
12. · Initiation and Progression of Atheroma Plaque
13. · Milestones in Cardiovascular Epidemiology: The Framingham Heart Study
14. · Emerging Biomarkers and Clinical Risk Metrics
15. Cancer Epidemiology
16. · Etiology and Classification of Carcinogens by the IARC
17. · Molecular Mechanisms of Damage from Key Carcinogens
18. · Oncological Surveillance Systems: The Cancer Registry
19. Diabetes Mellitus type 2 (T2DM) and Metabolic Syndrome
20. · Genomic Architecture of NCDs: Genome-Wide Association Studies (GWAS)
21. · Pathophysiology of Micro and Macrovascular Complications of Diabetes
22. Chronic Respiratory Diseases
23. · Impact of Particulate Material ($PM_{2.5}$ and $PM_{10}$) on the Lung Parenchyma
24. · Pathophysiology of COPD and Airway Remodeling
25. Neurodegenerative and Mental Health Diseases
26. · Molecular Pathogenesis of Alzheimer's Disease
27. · Neuroinflammation and Microbiota-Gut-Brain Axis
28. Chronic Kidney and Osteoarticular Diseases
29. · The Pathophysiological Crossroads of Cardiorenal Syndrome
30. · Epidemiology of Frailty
31. Epidemiological Research Methodology in NCDs
32. · Mathematical Models and Multivariate Analysis
33. · Mendelian Randomization
34. · Causal Inference and Bradford Hill Criteria
35. · Bias Control in NCD Epidemiology
36. Epidemiological Surveillance Systems for Chronic Diseases
37. · The STEPS Methodology of the World Health Organization
38. · Data Sources and Passive Surveillance Systems
39. Levels of Prevention and the Geoffrey Rose Paradox
40. · The Classic and Emerging Taxonomy of Prevention
41. · The Prevention Paradox by Geoffrey Rose
42. Global Public Policies and Action Frameworks
43. · The World Health Organization's "Best Buys" Interventions
44. Health Economics and Impact of NCDs
45. · Types of Health Economic Evaluation Analysis
46. · Individual and Family Financial Toxicity