Medically Important Spirochetes: Treponema pallidum, Borrelia, and Leptospira — Medical Microbiology

Microbiology · Basic Sciences

How it begins

Stages of syphilis, non-treponemal and treponemal tests, Jarisch-Herxheimer reaction, Lyme disease and erythema migrans, leptospirosis and Weil syndrome.

What it covers

1. 1. Biology and Unique Structure of the Spirochetes
2. 2. Treponema pallidum: Clinical Stages of Acquired and Congenital Syphilis
3. 3. Serological Diagnosis of Syphilis: Treponemal vs Non-treponemal Tests
4. 4. Borrelia burgdorferi: Lyme Disease and Erythema Migrans
5. 5. Leptospira interrogans: Leptospirosis and Weil Syndrome
6. 6. Reading Syphilis Serology over Time
7. · Traditional vs. reverse algorithm
8. 7. 2021–2025 Update
9. · Syphilis
10. · Relapsing fever Borrelia and Borrelia miyamotoi
11. · Leptospirosis
12. 8. Reasoned Clinical Cases
13. 9. Common Mistakes and Exam Pearls
14. 10. References and Sources for Further Reading