Geriatric Pharmacology — Advanced Reference of Geriatric Medicine

Pharmacology · Clinical Bases

How it begins

Comprehensive analysis of the pharmacokinetic, pharmacodynamic and biological changes of aging, evaluation of polypharmacy, therapeutic appropriateness criteria and deprescribing algorithms based on scientific evidence.

What it covers

1. Geriatric Pharmacology
2. Physiology and Pharmacokinetics
3. · Gastrointestinal Absorption
4. · Body Distribution
5. · Binding to Plasma Proteins
6. · Hepatic Metabolism
7. · Renal Excretion
8. Pharmacodynamic Changes
9. · Alteration in Receptor Sensitivity
10. · Loss of Homeostatic Reserve
11. Drug-Related Geriatric Syndromes
12. · 1. Delirium and Acute Cognitive Impairment
13. · 2. Falls and Osteoporotic Fractures
14. · 3. Sphincter Dysfunction
15. Polypharmacy and Prescription Cascade
16. · Definition and Dimension of the Problem
17. · The Prescription Cascade
18. Therapeutic Adequacy Criteria
19. · Beers Criteria (American Geriatrics Society - Latest Version)
20. · STOPP/START criteria (Version 3, pan-European)
21. Anticholinergic Load
22. · Physiopathological Bases and Receptors
23. · Anticholinergic Load Measurement Scales
24. Cardiovascular and Renal Pharmacology
25. · Antihypertensives in the Elderly
26. · Anticoagulation in the Geriatric Patient with Atrial Fibrillation (AF)
27. · Adjustment of Critical Drugs in Senile Renal Failure
28. Pharmacology of the Central Nervous System
29. · Antipsychotics in Patients with Dementia
30. · Antidepressants: Selection and Monitoring of Complications
31. Analgesia and Endocrine Pharmacology
32. · Approach to Chronic Pain in the Geriatric Patient
33. · Endocrine Pharmacology: The Strict Control of Type 2 Diabetes
34. Practical Deprescribing Algorithm
35. · Prevention of Withdrawal Syndromes and Rebound Effect
36. Clinically Critical Drug Interactions
37. · Serious Drug-Drug Interactions
38. · Critical Drug-Disease Interactions
39. Comprehensive Geriatric Evaluation and Follow-up Plan
40. · VGI Applied to Pharmacology
41. · Care Transition and Pharmacological Conciliation