Neonatal Gastroenterology and Hepatology — High Complexity Neonatology

Neonatology · Clinical Specialties

How it begins

Advanced and exhaustive study of the physiology of digestive development, necrotizing enterocolitis, structural anomalies with surgical resolution, complex cholestasis, alloimmune liver failure, motility disorders and intestinal failure in the newborn.

What it covers

1. Embryology and Physiology of Gastrointestinal Development
2. · 1.1 Embryological Development of the Digestive Tube and Intestinal Rotation
3. · 1.2 Neurogastroenterology, Mucosal Barrier Development and GALT
4. · 1.3 Digestion, Absorption and Nutritional Physiology of the Newborn
5. · 1.4 Establishment of the Neonatal Microbiome and the Role of HMOs
6. Necrotizing Enterocolitis (NEC) and Spontaneous Intestinal Perforation
7. · 2.1 Molecular Pathogenesis of NEC: The Role of TLR-4, Ischemia and Dysbiosis
8. · 2.2 Modified Bell Criteria for the Clinical Classification of NEC
9. · 2.3 Advanced Diagnostic Imaging: Radiology and Doppler Ultrasound
10. · 2.4 Medical-Surgical Management and Prevention Protocols for NEC
11. · 2.5 Spontaneous Intestinal Perforation (SIP) vs. Necrotizing Enterocolitis
12. Congenital Anomalies of the Gastrointestinal Tract
13. · 3.1 Esophageal Atresia and Tracheoesophageal Fistula
14. · 3.2 Duodenal, Jejunal and Ileal Atresias: Pathogenesis and Diagnosis
15. · 3.3 Meconium Ileus and Meconium Plug Syndrome
16. · 3.4 Intestinal Malrotation and Midgut Volvulus: Urological Hyperurgency
17. · 3.5 Abdominal Wall Defects: Gastroschisis vs. Omphalocele
18. · 3.6 Neonatal Hirschsprung Disease: Genetic Pathophysiology and Diagnosis
19. Neonatal Cholestasis and Liver Failure
20. · 4.1 Pathophysiology of Bilirubin Metabolism and Postnatal Transition
21. · 4.2 Biliary Tract Atresia (BA): Pathogenesis, Clinical Presentation, Diagnosis and Portoenterostomy
22. · 4.3 Alagille Syndrome and Ductal Hypoplasia
23. · 4.4 Infections and Idiopathic Neonatal Hepatitis
24. · 4.5 Inborn Errors of Metabolism with Neonatal Liver Expression
25. · 4.6 Gestational Alloimmune Hepatopathy (GALD) / Neonatal Hemochromatosis
26. · 4.7 IFALD (Intestinal Failure-Associated Liver Disease) and Toxicity of Soy Emulsions
27. Dysmotility, Functional Disorders and Digestive Allergies
28. · 5.1 Gastroesophageal Reflux (GER) vs. Reflux Disease (GERD) in Premature Babies
29. · 5.2 Food Intolerance and Management of Gastric Residues
30. · 5.3 Neonatal Food Allergies: CMA and FPIES Syndrome
31. Short Bowel Syndrome and Intestinal Failure
32. · 6.1 Biology of Intestinal Adaptation and Molecular Receptors
33. · 6.2 Multidisciplinary Management of Intestinal Failure and Systemic Complications
34. · 6.3 Advanced Pharmacological Therapeutics and Surgical Lengthening Procedures
35. Technological Vanguard and Future Research
36. · 7.1 Monitoring with Splanchnic NIRS and Ultrasensitive Biomarkers
37. · 7.2 Intestinal Organoids, Stem Cells and Regenerative Medicine