Histology: Peripheral Blood and Hematopoietic System

Histology: Peripheral Blood and Hematopoietic System — Expert Guide

How it begins

Blood is a specialized connective tissue whose "extracellular matrix" is plasma—a liquid medium—and whose "cellular elements" are the formed elements: erythrocytes, leukocytes and platelets. Unlike solid connective tissue, blood is a circulating tissue that physiologically connects all other tissues and organs in the body. The total blood volume in the adult is approximately 5–6…

What it covers

1. Blood as a Specialized Connective Tissue
2. Blood Plasma: Composition and Function
3. Erythrocytes (Red Blood Cells / Red Blood Cells)
4. · Morphology and Structure of the Membrane
5. · Hemoglobin: Structure, Function and Variants
6. · Mature Erythrocyte Metabolism
7. · Erythrocyte Life Cycle
8. Leukocytes: Morphology and Function
9. · Neutrophils
10. · Eosinophils
11. · Basophils
12. · Lymphocytes
13. · Monocytes
14. Platelets (Thrombocytes)
15. · Platelet Ultrastructure
16. · Platelet Activation and Primary Hemostasis
17. Hematopoiesis: From the Stem Cell to the Mature Cells
18. · Hematopoietic Stem Cells (HSC) and Hematopoietic Hierarchy
19. · Erythropoiesis: From Proerythroblast to Reticulocyte
20. · Granulopoiesis (Myelopoiesis): From Myeloblast to PMN
21. · Monocytopoiesis
22. · Megakaryocytopoiesis and Thrombopoiesis
23. · Lymphopoiesis
24. Bone Marrow: Histology of the Hematopoietic Organ
25. · Red Marrow vs. Yellow Marrow
26. · Hematopoietic Niches
27. · Myeloid:Erythroid Ratio (M:E)
28. Molecular Regulation of Hematopoiesis
29. Peripheral Blood Smear: Normal Morphology and Alterations
30. Major Clinical Correlations
31. · Classification of Anemias
32. · Polycythemia Vera and Polyglobulia
33. · Acute Leukemias
34. · Chronic Myeloproliferative Neoplasms (CMP)
35. · Myelodysplastic syndrome (MDS)
36. · Main Platelet Dyscrasias
37. Histological and Diagnostic Techniques