Epistemis

Intensive Medicine: Sepsis, Serious Infections and Multiple Organ Dysfunction - Neurointensive and Critical Reference Treatise

Intensive Medicine · Clinical Specialties

How it begins

Molecular pathophysiology of the pattern recognition receptor, immunothrombosis, microcirculatory dysfunction, mitochondrial medicine, advanced hemodynamic monitoring and targeted immunomodulation in the Intensive Care Unit.

What it covers

  1. · Pattern Recognition Receptors (PRR) and Cellular Signaling
  2. · Interaction between Coagulation and Inflammation: Immunothrombosis
  3. · The Concept of Cytopathic Hypoxia and Mitochondrial Dysfunction
  4. · The Conceptual Transition: Sepsis-1 to Sepsis-3
  5. · The Hemodynamic Physiology of Septic Shock
  6. · The Physiology of Septic Shock and the Fluid Paradox
  7. · Pharmacology of Cardiovascular Receptors in Sepsis
  8. · The Golden Rule of Antibiotherapy in Sepsis
  9. · Organic Systems and Specific Pathology
  10. · The Corticosteroid Debate in Septic Shock
  11. · The Pathophysiology of the Late Immunosuppression Phase

The complete study guide is in the app

This page summarizes the outline. The full interactive study guide —with high-yield diagrams, clinical tables, and board review cases— can be read inside Epistemis, completely offline and ad-free.

Subject
Intensive Medicine
Category
Clinical Specialties
Type
Study Guide
Sections
11
Reviewed
2026-09-03
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