Epistemis

Internal Medicine: Pathology of the Spinal Cord

Neurology · Clinical Specialties

How it begins

Comprehensive study of functional anatomy, major spinal syndromes, the pathophysiology of spinal cord damage and the main diseases that affect the spinal cord, with emphasis on differential diagnosis and highly relevant clinical correlations.

What it covers

  1. Functional Anatomy of the Spinal Cord
  2. · Macro-Anatomy: Dimensions and Segmentation
  3. · Microscopy: Gray Matter and White Matter
  4. · Medullary Vascularization: The Key to Vascular Syndromes
  5. · Spinal Meninges and Cerebrospinal Fluid
  6. Classic Spinal Cord Syndromes
  7. · Brown-Séquard Syndrome (Medullary Hemisection)
  8. · Anterior Medullary Syndrome (Anterior Spinal Artery)
  9. · Central Cord Syndrome
  10. · Posterior spinal cord syndrome
  11. · Conus Medullaris Syndrome
  12. · Cauda equina syndrome
  13. · Complete Spinal Injury Syndrome vs. Incomplete
  14. Pathophysiology of Spinal Cord Damage
  15. · Primary Injury vs. Secondary Injury
  16. · Axonal Regeneration Inhibitors: Molecular Barriers
  17. · Medullary Shock vs. Neurogenic Shock
  18. Multiple Sclerosis and NMOSD / MOGAD
  19. · Pathophysiology of MS
  20. · Clinical Forms of MS and McDonald Criteria 2017
  21. · The Spinal Cord in MS: Semiological and Radiological Characteristics
  22. · NMOSD (Neuromyelitis Optica Spectrum Disease)
  23. Transverse Myelitis
  24. · TM Diagnostic Criteria (TMCWG 2002)
  25. · Etiology of Transverse Myelitis
  26. Medullary Vascular Pathology
  27. · Medullary Infarction (Medullary Stroke)
  28. · Medullary Vascular Malformations
  29. · Foix-Alajouanine Syndrome (Subacute Necrotizing Angioma)
  30. Spinal Cord Compression: Causes and Management
  31. · Topographic Classification of Compression Injuries
  32. · Spinal Epidural Metastasis (MSCC): Oncological Emergency
  33. · Cervical Spondylotic Myelopathy (CSM)
  34. Spinal cord trauma
  35. · Biomechanical Mechanisms of Injury
  36. · ASIA Impairment Scale (AIS): Complete System
  37. · Acute Management of Spinal Cord Trauma
  38. · Complications of Chronic Spinal Cord Trauma
  39. Syringomyelia and Syringobulbia
  40. · Pathophysiology: The Theory of Williams and Gardner
  41. · Etiology of Syringomyelia
  42. · Clinical Presentation and Semiology
  43. Degenerative Motor Neuron Diseases
  44. · Amyotrophic Lateral Sclerosis (ALS / SLA / ALS)
  45. · Spinal Muscular Atrophy (SMA / SMA) and Kennedy Syndrome
  46. Medullary Infectious Pathology
  47. · Acute Flaccid Myelitis (AMF / AFM): The "New Polio"
  48. · HTLV-1 myelopathy (TSP/HAM)
  49. · Spinal Epidural Abscess (SEA): Neurosurgical Emergency
  50. · Spinal Tuberculosis (Pott's Disease)
  51. Nutritional and Toxic Myelopathy
  52. · Subacute Combined Spinal Degeneration (SCD)
  53. · Myelopathy due to Nitrogen Protoxide (N₂O)
  54. Spinal Cord Tumors
  55. · Topographic Classification and General Characteristics
  56. · Leptomeningeal Carcinomatosis (Leptomeningeal Metastases)
  57. Multidisciplinary Diagnosis and Management
  58. · Spinal Cord MRI: Protocols and Interpretation
  59. · Lumbar Puncture and Interpretation of CSF in Spinal Pathology
  60. · Functional Scales in Spinal Pathology
  61. · Management of Chronic Complications of Myelopathies

The complete study guide is in the app

This page summarizes the outline. The full interactive study guide —with high-yield diagrams, clinical tables, and board review cases— can be read inside Epistemis, completely offline and ad-free.

Subject
Neurology
Category
Clinical Specialties
Type
Study Guide
Sections
61
Reviewed
2026-08-02
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