Epistemis

Neonatology — Advanced Neonatal Infectology

Neonatology · Clinical Specialties

How it begins

Comprehensive and subspecialty level analysis of the pathophysiology, molecular diagnosis and treatment schemes of infectious processes in the neonatal period. It includes a detailed approach to early and late sepsis, meningitis, systemic viral and fungal infections, osteoarticular pathology, necrotizing enterocolitis and pharmacokinetics adapted to the critically ill neonate.

What it covers

  1. Immunobiology of Neonatal Development
  2. · Humoral Immunity: The Critical Role of Placental Transfer of IgG
  3. · Cellular and Barrier Immunity
  4. · Signaling by Pattern Recognition Receptors (PRRs)
  5. Early-Onset Sepsis - EOS
  6. · Contemporary Microbiology of Early Sepsis
  7. · Clinical Risk Factors and Chorioamnionitis
  8. · The Neonatal Sepsis Calculator (Kaiser Permanente Sepsis Calculator)
  9. Late Neonatal Sepsis (Late-Onset Sepsis - the)
  10. · Pathophysiology: Broken Barriers and Invasive Devices
  11. · Microbiology of Late Nosocomial Sepsis
  12. Diagnosis and Biomarkers of Sepsis
  13. · Clinical Manifestations of Suspected Septic
  14. · Front-Line Laboratory Testing and Biomarker Kinetics
  15. · Complete Blood Count Evaluation: The I/T Index (Immature/Total)
  16. · Molecular Biology Diagnosis: Multiplex PCR Panels
  17. Pharmacokinetics and Pharmacodynamics (PK/PD) in the Critical Neonate
  18. · Neonatal Pharmacokinetics Physiology
  19. · Hepatic Metabolism and Enzymatic Immaturity
  20. · Reference Neonatal Dosing Schemes in Infectology
  21. Vertically Transmitted Infections (TORCH) — Part I
  22. · Congenital Cytomegalovirus (CMV): Pathophysiology and Cellular Damage
  23. · Congenital Toxoplasmosis: The Sabin Tetrad
  24. Vertically Transmitted Infections (TORCH) — Part II
  25. · Congenital Syphilis: Pathophysiology of Tissue Invasion
  26. · CDC Diagnostic Algorithm for Congenital Syphilis
  27. · Congenital Rubella Syndrome (CRS): Gregg's Triad
  28. Herpes Simplex Virus (HSV) and Varicella-Zoster in the Neonate
  29. · Neonatal Herpes Simplex Virus (HSV) Infection
  30. · Clinical Classification of Neonatal HSV Infection
  31. · Neonatal and Perinatal Chickenpox
  32. Invasive Fungal Infections in the NICU
  33. · Pathophysiology of Invasive Candidiasis in Premature Babies
  34. · Antifungal Treatment in the Neonatal Period
  35. Neonatal Meningitis and Ventriculitis
  36. · Pathophysiology: Crossing the Blood-Brain Barrier (BBB)
  37. · Diagnosis Using Lumbar Puncture: Interpretation of CSF
  38. · Neonatal Ventriculitis: The Feared Complication
  39. Neonatal Pneumonia and Pneumonia Associated with Mechanical Ventilation (VAP)
  40. · Congenital and Acquired Intrapartum Pneumonia
  41. · Pneumonia Associated with Mechanical Ventilation (MAP) in the NICU
  42. · Diagnosis of VAP in Neonates (Modified CDC Criteria)
  43. · Atypical Pathogens and Pneumonia of Prematurity
  44. Osteomyelitis, Septic Arthritis and Osteoarticular Infections
  45. · Pathophysiology of Neonatal Bone Dissemination
  46. · Clinical Presentation and Index of Suspicion
  47. · Microbiology and Diagnostic Approach
  48. Necrotizing Enterocolitis (NEC) and Intra-abdominal Infection
  49. · Pathophysiology: The Triad of Necrotizing Enterocolitis
  50. · Bell Clinical Stages Modified by Walsh and Kliegman
  51. Epidemiology, Prevention and Control of Outbreaks in the NICU
  52. · Antimicrobial Optimization Programs (PROA / Stewardship)
  53. · Evidence-Based Prevention Strategies: Care Bundles

The complete study guide is in the app

This page summarizes the outline. The full interactive study guide —with high-yield diagrams, clinical tables, and board review cases— can be read inside Epistemis, completely offline and ad-free.

Subject
Neonatology
Category
Clinical Specialties
Type
Study Guide
Sections
53
Reviewed
2026-08-02
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