Prions, Biosafety, and Sterilization Methods — Medical Microbiology

Microbiology · Basic Sciences

How it begins

Pathological PrPSc, Creutzfeldt-Jakob disease, Spaulding classification, autoclaving, prion inactivation, and BSL-1 to BSL-4 levels.

What it covers

1. 1. Biology and Molecular Mechanism of Prions
2. 2. Human Prion Diseases: Creutzfeldt-Jakob and Fatal Familial Insomnia
3. 3. Sterilization and Disinfection: Spaulding's Rational Classification
4. 4. Physical and Chemical Methods and the Prion Inactivation Protocol
5. 5. Laboratory Biosafety Levels (BSL-1 to BSL-4)
6. 6. Deciding How to Reprocess an Instrument
7. 7. Update: Diagnosis of Prion Diseases and Biosafety
8. 8. Reasoned Clinical Cases
9. 9. Common Mistakes and Exam Pearls
10. 10. References and Sources for Further Reading