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Psychiatry: Neurodevelopmental Disorders — Treatise on Specialized Medicine

Psychiatry · Clinical Specialties

How it begins

Detailed structural, pathophysiological, genetic and psychopharmacological analysis of maturational deviations of the central nervous system. Dimensional diagnosis strategies and transdiagnostic therapeutic approach.

What it covers

  1. Neurodevelopmental Disorders
  2. Introduction and Developmental Neurobiology
  3. · Ontogeny of the Nervous System and Critical Periods
  4. · Global Magnitude and Burden of Disease
  5. · Temporal Interdependence and Synaptic Plasticity
  6. DSM-5-TR and ICD-11 Classification
  7. · Compared Classification Systems
  8. · Limitations of Categorical Systems and the RDoC Project
  9. Genetics and Epigenetics
  10. · Genomic Architecture: Common and Rare Variability
  11. · Variations in the Number of Copies (CNVs) and Microdeletions / Microduplications
  12. · Epigenetics: Influence of the Environment on Gene Expression
  13. ASD: Pathophysiology and Brain Connectivity
  14. · The Excitation/Inhibition (E/I) Imbalance Hypothesis
  15. · Aberrant Connectivity Models: Theory of Central Incoherence
  16. · Dysfunction in Intrinsic Connectivity Networks
  17. · The Mirror Neuron System (SNE)
  18. ASD: Clinical Manifestations and Phenotypes
  19. · Nuclear Symptoms according to DSM-5-TR Criteria
  20. · Severity Level Stratification
  21. · Phenotypic Gender Differences: Clinical Masking (Camouflage)
  22. ASD: Differential Diagnosis and Comorbidities
  23. · Standardized Diagnostic Instruments
  24. · Exhaustive Differential Diagnosis
  25. · Medical and Psychiatric Comorbidities
  26. ADHD: Neurotransmission and Attention Networks
  27. · Neurotransmission Systems Involved: Dopamine and Norepinephrine
  28. · Dysfunction in Large-Scale Attentional Networks
  29. · Striatal Projection and Psychomotor Control Pathways
  30. ADHD: Clinical Presentations and Course
  31. · Clinical Presentations according to DSM-5-TR
  32. · Clinical Course Throughout the Life Cycle
  33. ADHD: Complete Therapeutic Approach
  34. · Pharmacotherapy: Stimulants
  35. · Pharmacotherapy: No Stimulants
  36. · Psychotherapeutic and Behavioral Intervention
  37. Intellectual Disability (Intellectual Development Disorder)
  38. · Assessment of Adaptive Functioning: The Three Domains
  39. · Etiology and Differential Diagnosis of Intellectual Disability
  40. Learning and Communication Disorders
  41. · Specific Learning Disorder
  42. · Communication Disorders
  43. Gilles de la Tourette Disorder and Tics
  44. · Definition and Diagnostic Criteria DSM-5-TR
  45. · Pathophysiology: Dysfunction of the Cortico-Striato-Thalamo-Cortical Circuits (CSTC)
  46. · Sensory Phenomenology: The Premonitory Impulse
  47. · Tourette's Triad: Syndromic Comorbidities
  48. · Pharmacological and Behavioral Intervention Strategies
  49. Motor Coordination and Stereotypies
  50. · Developmental Coordination Disorder (DCD)
  51. · Stereotyped Movement Disorder
  52. Transition to Adulthood and Intervention Models
  53. · The Service Transition Gap (Aging Out)
  54. · Evidence-Based Intervention Models
  55. · Advances in Pharmacogenomics and Precision Psychiatry
  56. · The Neurodiversity Paradigm

The complete study guide is in the app

This page summarizes the outline. The full interactive study guide —with high-yield diagrams, clinical tables, and board review cases— can be read inside Epistemis, completely offline and ad-free.

Subject
Psychiatry
Category
Clinical Specialties
Type
Study Guide
Sections
56
Reviewed
2026-08-02
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