Antimicrobial Resistance, Susceptibility Testing, and Stewardship — Medical Microbiology

Microbiology · Basic Sciences

How it begins

Molecular mechanisms of resistance, ESBL, AmpC, carbapenemases, ESCAPE pathogens, interpreted reading of the CLSI/EUCAST antibiogram and PROA programs.

What it covers

1. 1. Biochemical and Molecular Mechanisms of Antimicrobial Resistance
2. · The Four Fundamental Biochemical Mechanisms
3. 2. Classification of Beta-Lactamases: Penicillinases, ESBL, AmpC and Carbapenemases
4. 3. Critical Priority Pathogens (ESKAPE Group)
5. 4. The Antibiogram: Disk Diffusion, Microdilution and CLSI/EUCAST Committees
6. · Definition of Clinical Categories according to EUCAST
7. 5. Interpretive Reading of the Antibiogram
8. 6. Antimicrobial Stewardship Programs (ASP / Stewardship)
9. 7. Resistance Genomics and Ambler Molecular Classification of Beta-Lactamases
10. 8. From Phenotype to Mechanism to Treatment
11. 9. WHO Bacterial Priority Pathogens List (2024)
12. 10. Antimicrobial Stewardship: Tools That Work
13. 11. Reasoned Clinical Cases
14. 12. Common Mistakes and Exam Pearls
15. 13. References and Sources for Further Reading