Sepsis, Septic Shock, and Infective Endocarditis — Medical Microbiology

Microbiology · Basic Sciences

How it begins

Definitions of Sepsis-3, SOFA and qSOFA scales, endothelial pathophysiology, bundle of the first hour with norepinephrine and Duke criteria in endocarditis.

What it covers

1. 1. Sepsis-3 International Consensus Definitions: Sepsis and Septic Shock
2. 2. Assessment Scores: Bedside qSOFA and the Full SOFA Score
3. 3. Pathophysiology: Endothelial Dysfunction, Immunothrombosis and Immune Paralysis
4. 4. The "Hour-1 Bundle" (Surviving Sepsis Campaign)
5. 5. Bacteremia and Infective Endocarditis: Modified Duke Criteria (updated in 2023 as Duke-ISCVID)
6. 6. The First Hour according to the Surviving Sepsis Campaign 2021
7. 7. What's New: Pediatric Sepsis and Endocarditis
8. · Phoenix criteria for pediatric sepsis (2024)
9. · Endocarditis: 2023 Duke-ISCVID criteria and the 2023 ESC guideline
10. 8. Practical Management of Bacteremia
11. 9. Reasoned Clinical Cases
12. 10. Common Mistakes and Exam Pearls
13. 11. References and Sources for Further Reading