Benign Disorders of Leukocytes and Lymph Nodes — Internal Medicine · Expert Reference Guide
Internal Medicine · Clinical Specialties
How it begins
Comprehensive guide to benign (reactive, non-neoplastic) disorders of white blood cells and the lymphatic system: quantitative and qualitative abnormalities of neutrophils, eosinophils, basophils, monocytes and lymphocytes; mononucleosis syndromes; and the approach to lymphadenopathy and splenomegaly. Subspecialty level.
What it covers
- Hematopoiesis of the white series and leukocyte kinetics
- · Neutophile compartments
- · Adult reference values
- The leukogram and the peripheral blood smear
- · Deviation to the left and variants
- · Pseudoalterations and artifacts
- Neutrophilia
- · Mechanisms and etiologies
- · Leukemoid reaction vs CML vs chronic idiopathic neutrophilia
- Neutropenia and agranulocytosis
- · Etiological classification
- Eosinophilia and basophilia
- · Eosinophilia: gradation and causes
- · Hypereosinophilic syndrome (HES)
- · Basophilia
- Monocytosis and monocytopenia
- · Monocytosis ( 1.0x10⁹/L)
- Reactive lymphocytosis
- · Causes of lymphocytosis
- Lymphopenia
- · Etiologies
- Infectious mononucleosis and mononucleosis syndrome
- · EBV infectious mononucleosis
- · Differential diagnosis of mononucleosis syndrome
- Benign morphological and functional anomalies
- · Hereditary-constitutional morphological anomalies
- · Inclusions and reactive findings
- · Relevant benign functional defects
- Lymphadenopathy: approach to benign adenopathic syndrome
- · Mechanisms of lymph node increase
- · Semiological evaluation of lymph node characteristics
- · Location and drainage topographic value
- · Generalized vs localized
- Lymphadenitis and benign lymphadenopathy with its own name
- Splenomegaly and hypersplenism
- · Mechanisms of splenomegaly
- · Hypersplenism
- Integrated boarding and emergencies
- · Reasoning algorithm
- · Two emergencies that cannot wait
The complete study guide is in the app
This page summarizes the outline. The full interactive study guide —with high-yield diagrams, clinical tables, and board review cases— can be read inside Epistemis, completely offline and ad-free.
- Subject
- Internal Medicine
- Category
- Clinical Specialties
- Type
- Study Guide
- Sections
- 40
- Reviewed
- 2026-08-02