Pigmentation Disorders — Medical Dermatology

Dermatology · Clinical Specialties

How it begins

Comprehensive analysis of the molecular mechanisms of melanogenesis, congenital and acquired pigmentation alterations, their pathophysiology, differential diagnosis and current therapeutic options.

What it covers

1. Biology of the Melanocyte and the Epidermal Unit of Melanization
2. · Origin in the Neural Crest and Cellular Specification
3. · Structure of the Mature Melanocyte
4. · Types of Melanin and Determinants of Phototype
5. Melanogenesis: Biochemistry and Biogenesis of Melanosomes
6. · The Biochemical Pathway of Melanogenesis
7. · Biogenesis of Melanosomes: The Four Stages
8. · Hormonal and Environmental Regulation of Melanogenesis
9. General Classification of Pigmentation Disorders
10. Vitiligo
11. · Pathophysiology: The Autoimmune Model
12. · Genetics of Vitiligo
13. · Clinical Classification of Vitiligo
14. · Diagnosis
15. Albinism: Types, Genetics and Systemic Manifestations
16. · Oculocutaneous Albinism (OCA): Seven Types
17. · Ocular Manifestations of Albinism
18. · Albinism Syndromes with Systemic Commitment
19. · Dermatological Management of Albinism
20. Other Relevant Hypopigmentations
21. Melasma (Chloasma)
22. · Pathophysiology of Melasma
23. · Depth Classification
24. Ephelides, Lentigo and Coffee with Milk Spots
25. Post-Inflammatory Hyperpigmentation (PIH)
26. · Pathophysiological Mechanism
27. · Treatment of PIH
28. Other Relevant Acquired Hyperpigmentation
29. Hyperpigmentation of Systemic and Endocrine Origin
30. · Addison's Disease (Primary Adrenal Insufficiency)
31. · Cushing's Syndrome and Paradoxical Pigmentation
32. · Argyria, Chrysoderma and Exogenous Pigmentations
33. Melanocytic Nevi: Classification, Molecular Biology and Risk of Melanoma
34. · Histological Classification
35. · Molecular Biology of Melanocytic Transformation
36. Depigmentation Treatments: Comparative Mechanisms of Action
37. Integrating Differential Diagnosis and Diagnostic Tools
38. · Essential Diagnostic Tools
39. · Algorithm for Differential Diagnosis of Hypopigmented Lesions
40. · Algorithm for Differential Diagnosis of Facial Hyperpigmented Lesions