Treaty on Neurointensivism and Advanced Neuromonitoring | Advanced Medical Library

Intensive Medicine · Clinical Specialties

How it begins

An exhaustive and rigorous compendium on the management of neurocritical patients. From the intrinsic mechanisms of autoregulation of cerebral blood flow and Monro-Kellie dynamics, to the frontiers of metabolic monitoring by microdialysis, refractory status epilepticus, post-arrest temperature control, targeted therapies in severe head trauma and the systemic pathophysiology of death...

What it covers

1. Neurointensivism and Neurological Support
2. Applied Brain Physiology and Regulation of Cerebral Blood Flow (CBF)
3. · 1.1 · Flow-Metabolism Coupling and Oxygen Consumption
4. · 1.2 · Cerebral Autoregulation: Curves, Limits and Transducer Mechanisms
5. · 1.3 · The Blood-Brain Barrier (BBB): Ultrastructure and Transport Dynamics
6. Pathophysiology of Intracranial Hypertension (ICH)
7. · 2.1 · Extended Monro-Kellie Dynamics and Compliance Curve
8. · 2.2 · Types of Cerebral Edema: Vasogenic, Cytotoxic, Interstitial and Osmotic
9. · 2.3 · Cerebral Herniation Syndromes and Tissue Displacement Dynamics
10. Monitoring of Intracranial Pressure (ICP) and Cerebral Perfusion Pressure (CPP)
11. · 3.1 · Registration Methods: Intraventricular Catheter vs. Intraparenchymal Sensors
12. · 3.2 · ICP Wave Analysis: Components and Meaning
13. · 3.3 · Pathological Lundberg Waves (A, B and C)
14. · 3.4 · Optimal Cerebral Perfusion Pressure (PPCopt) and the Concept of Dynamic Autoregulation
15. Advanced Neurophysiological and Metabolic Monitoring
16. · 4.1 · Oxygen Saturation in the Jugular Bulb (SjvO₂)
17. · 4.2 · Tissue Oxygen Pressure (PtiO₂)
18. · 4.3 · Markers of Brain Microdialysis
19. · 4.4 · Continuous Electroencephalogram (cEEG) in the ICU
20. · 4.5 · Transcranial Doppler (TCD) and its Hemodynamic Indices
21. Severe Traumatic Brain Injury (gTBI) and BTF Guidelines
22. · 5.1 · Pathophysiology: Primary Damage vs. Secondary Damage
23. · 5.2 · Brain Trauma Foundation (BTF) Guidelines - 4th Edition
24. · 5.3 · Intracranial Hypertension Treatment Algorithm
25. Acute Ischemic Cerebrovascular Attack (CVA)
26. · 6.1 · Pathophysiology of the Core of Ischemic Infarction
27. · 6.2 · Reperfusion Therapy: Systemic Thrombolysis and Mechanical Thrombectomy
28. · 6.3 · Blood Pressure Management in Acute Ischemic Stroke
29. · 6.4 · Malignant Cerebral Infarction of the MCA and Decompressive Craniectomy
30. Aneurysmal Subarachnoid Hemorrhage (aSAH)
31. · 7.1 · Clinical and Imaging Stratification (Hunt-Hess and Modified Fisher)
32. · 7.2 · Definitive Exclusion of Aneurysm: Surgical Clipping vs. Endovascular Coiling
33. · 7.3 · Critical Complications and Their Pathophysiological Management
34. Spontaneous Intracerebral Hemorrhage (ICH)
35. · 8.1 · Pathophysiology: Hematoma Expansion and Perihematomal Edema (PHE)
36. · 8.2 · Blood Pressure Control: INTERACT2 and ATACH-II Trials
37. · 8.3 · Immediate Reversal of Specific Coagulopathies
38. · 8.4 · Surgery in ICH: STICH, STICH II and MISTIE III trials
39. Convulsive and Nonconvulsive Status Epilepticus (SE)
40. · 9.1 · Pathophysiology of GABA-A Receptor Refractoriness
41. · 9.2 · Stepped Pharmacological Treatment Protocol in the ICU
42. · 9.3 · Super-Refractory Status Epilepticus (SESR)
43. Anoxic and Hypoxic Encephalopathy Post-Cardiac Arrest
44. · 10.1 · Pathophysiology of Global Ischemia and Reperfusion Cascade
45. · 10.2 · Target Temperature Management (TTM)
46. · 10.3 · Multimodal Neuroprognostic Algorithm
47. Serious Central Nervous System Infections in the ICU
48. · 11.1 · Pharmacokinetic Barriers of the Inflamed BBB
49. · 11.2 · Etiology and Empirical Antibiotic Schemes in the UCIQ
50. Neuromuscular Crises in the ICU, Dysautonomia and Acquired Weakness
51. · 12.1 · Intubation and Mechanical Ventilation Criteria: The "20-30-40" Rule
52. · 12.2 · Autonomic Storm / Cerebral Sympathetic Paroxysm
53. · 12.3 · Acquired Weakness in the Intensive Care Unit (ICUAW)
54. Brain Death and Management of Solid Organ Donors
55. · 13.1 · Clinical Criteria for Diagnosis and Apnea Testing
56. · 13.2 · Confirmatory Instrumental Tests
57. · 13.3 · Systemic Pathophysiology of Brain Death
58. Non-Invasive Neuromonitoring Based on Ultrasonography
59. · 14.1 · Ultrasound Measurement of the DVNO: Technique and Clinical Thresholds
60. Systemic Complications of the Neurocritical Patient
61. · 15.1 · Pathophysiology of Neurogenic Pulmonary Edema (NPE)
62. · 15.2 · Pathophysiology of Sodium Disorders: CSWS vs. SIADH
63. Sedoanalgesia, Humanization and Ventilatory Weaning in the Neurocritical Patient
64. · 16.1 · Propofol, Dexmedetomidine and the Problem of Benzodiazepine Use
65. · 16.2 · Ventilatory Weaning Algorithm in the Patient with Compromised Airway Reflexes
66. · 16.3 · Key Principles in the Clinical Practice of Neurointensivism