Epistemis

Emergencies: Pathology of the Airway and Parenchyma

Emergencies: Pathology of the Airway and Parenchyma — Expert Level Reference

How it begins

An exhaustive, medical subspecialty-level compendium on critical evaluation, molecular pathophysiology, stepwise treatment in emergencies, and ventilatory management of acute pathologies of the respiratory system.

What it covers

  1. Pathophysiology of acute respiratory failure and ventilatory mechanics
  2. · Mechanisms of Hypoxemia
  3. · Physiological shunt equation
  4. · Respiratory Mechanics and the Work of Breathing (WOB)
  5. Difficult airway approach and rapid intubation sequence
  6. · Difficult Airway Prediction (VAD)
  7. · Pharmacology of the Rapid Intubation Sequence (RSI)
  8. · Delayed Intubation Sequence (SID) and Physiological Optimization
  9. · Algorithm for Failed Airway
  10. Upper airway obstruction: diagnosis and immediate management
  11. · Anatomy and Flow Patterns
  12. · Highly Relevant Clinical Entities in Emergencies
  13. · Therapeutic Strategy in Emergencies
  14. Life-threatening asthma attack (status asthmaticus)
  15. · Pathophysiology of Air Trapping and Auto-PEEP
  16. · Severity Stratification in Emergencies
  17. · Stepped Emergency Medical Treatment
  18. · Invasive Mechanical Ventilation in Life-Risk Asthma
  19. Severe exacerbation of COPD and non-invasive ventilation
  20. · Pathophysiology of Acute Respiratory Acidosis over Chronic
  21. · Non-Invasive Ventilation (NIMV) — The Standard of Care
  22. · Adjuvant Pharmacological Treatment
  23. High flow oxygen therapy and interface selection in the emergency room
  24. · High Flow Nasal Cannula (HFNC) — Physiological Principles
  25. · Conventional Oxygen Therapy Systems versus High Flow
  26. · Iatrogenic Hyperoxemia in Emergencies
  27. Acute respiratory distress syndrome (ARDS): cellular mechanisms and phases
  28. · Berlin Criteria (Operational Definition)
  29. · Molecular and Ultrastructural Physiopathology
  30. · The Concept of "Baby Lung"
  31. ARDS: protective ventilation and rescue strategies
  32. · Pillars of Protective Mechanical Ventilation
  33. · Rescue Strategies in Moderate to Severe ARDS (PaO₂/FiO₂ 150)
  34. Severe community-acquired pneumonia (CAP)
  35. · Severity Stratification and ICU Admission Criteria
  36. · NACG Microbiological Spectrum
  37. · Broad Spectrum Empirical Antibiotherapy Scheme
  38. · Local and Systemic Complications
  39. High-risk (massive) pulmonary thromboembolism (PTE)
  40. · Pathophysiology of Acute Right Ventricular Failure
  41. · Risk Stratification according to ESC Guides
  42. · Bedside Echocardiography (POCUS) in Massive PET
  43. · Urgent Reperfusion Treatment
  44. Diffuse alveolar hemorrhage (DHA) and alveolar infiltrates
  45. · Pathophysiology of Alveolar-Capillary Disruption
  46. · Emergency Clinical Presentation
  47. · Diagnostic Approach in Emergencies
  48. · Stepped Therapeutic Management in Emergencies
  49. Fume inhalation and thermal-chemical injury to the airway
  50. · Pathophysiology of Inhalation Injury
  51. · Management of Systemic Chemical Asphyxia
  52. · Early Intubation Criteria
  53. Thoracic trauma: pulmonary contusion and tracheobronchial disruption
  54. · Pulmonary Contusion
  55. · Tracheobronchial Disruption
  56. Tension pneumothorax and flail chest
  57. · Tension Pneumothorax — The Pathophysiology of Obstructive Shock
  58. · Flail Chest
  59. Cardiopulmonary interactions and ventilator-induced injury (VILI)
  60. · Cardiopulmonary Interactions
  61. · Pathophysiology of VILI (Ventilator Induced Injury)
  62. · The Mechanical Potential (Mechanical Power)

The complete study guide is in the app

This page summarizes the outline. The full interactive study guide —with high-yield diagrams, clinical tables, and board review cases— can be read inside Epistemis, completely offline and ad-free.

Subject
Emergency
Category
Clinical Specialties
Type
Study Guide
Sections
62
Reviewed
2026-08-02
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