Toxicological Emergencies

Toxicological Emergencies — Expert Level Reference

How it begins

Expert-level reference guide for the cellular approach, analytical diagnosis, electrophysiological monitoring and advanced antidotic therapeutics of critical toxicological syndromes in emergency medicine.

What it covers

1. Initial assessment of the intoxicated patient and characterization of toxidromes
2. · Systematic characterization of cardinal toxidromes
3. Gastrointestinal decontamination and extracorporeal removal techniques
4. · 1. Activated Charcoal in Single Dose (CADU)
5. · 2. Gastric lavage
6. · 3. Total Intestinal Irrigation (TII)
7. · 4. Activated Charcoal in Multiple Doses (CADM)
8. · 5. Extracorporeal Cleansing Techniques
9. Paracetamol (Acetaminophen) Poisoning
10. · Cellular Pathophysiology and NAPQI Formation
11. · Clinical Phases of Hepatotoxicity
12. · Diagnostic Evaluation: Rumack-Matthew Nomogram
13. · Treatment Schemes with N-Acetylcysteine (NAC)
14. · King's College Criteria for Urgent Liver Transplantation
15. Salicylate Poisoning (Acetylsalicylic Acid)
16. · Cellular Pathophysiology and Uncoupling of Oxidative Phosphorylation
17. · Acid-Base Balance Disorders
18. · Clinical Manifestations and Neurotoxicity
19. · Therapeutic Approach and Risks of Intubation
20. Cardiovascular Toxins: Beta-blockers and Calcium Antagonists
21. · Pathophysiology of Beta-blocker Intoxication
22. · Pathophysiology of Calcium Antagonist Intoxication
23. · Stepped Therapeutic Approach and HIET Therapy
24. Digoxin and Cardiotonic Glycosides
25. · Cellular Pathophysiology and Electrical Conduction
26. · Clinical Manifestations: Acute vs. Chronic Intoxication
27. · Electrocardiographic Findings
28. · Antidotic Therapeutics: Specific Antibodies against Digoxin (Fab)
29. Tricyclic Antidepressants (TCA)
30. · Mechanism of Action of Multisystem Toxicity
31. · Prognostic Electrocardiographic Criteria
32. · Use of 8.4% Baking Soda
33. Neuromuscular Syndromes: Serotonergic vs Neuroleptic Malignant Syndrome
34. · Serotonin Syndrome: Hunter Diagnostic Criteria
35. · Neuroleptic Malignant Syndrome (NMS)
36. · Clinical and Therapeutic Differentiation
37. Toxic Alcohols: Methanol and Ethylene Glycol
38. · 1. Pathophysiology of Methanol Intoxication
39. · 2. Pathophysiology of Ethylene Glycol Poisoning
40. · 3. Gap Calculation: Anion Gap and Osmolar Gap
41. · 4. Antidotic and Clearance Therapeutic Approach
42. Carbon Monoxide and Cyanide
43. · 1. Carbon Monoxide Poisoning
44. · 2. Cyanide Poisoning
45. Acetylcholinesterase Inhibitors: Organophosphates and Carbamates
46. · Cellular Physiopathology and the Phenomenon of "Aging"
47. · Clinical Manifestations: Acute Cholinergic Toxidrome
48. · Antidotic Treatment Scheme
49. Corrosive Substances, Caustics and Heavy Metals
50. · 1. Caustic Poisoning: Acids vs. Alkalis
51. · 2. Heavy Metal Poisoning and Chelation Therapy
52. · Synthesis of Critical Toxicological Reasoning