Biochemistry: Clinical Applications

Biochemistry: Clinical Applications — Medicine

How it begins

Exhaustive integration between biochemical foundations and their translation to the diagnosis, pathophysiology and treatment of diseases. Highly complex medical requirement level.

What it covers

1. Clinical Applications
2. Clinical Enzymology and Serum Biomarkers
3. · Cardiac Markers
4. · Liver Markers
5. · Pancreatic Markers
6. Blood Gases and Acid-Base Balance
7. · Henderson-Hasselbalch Equation and Bicarbonate System
8. · Classification and Pathophysiology of Acid-Base Disorders
9. · Anion Gap: Differential Diagnosis of Metabolic Acidosis
10. · Oxygen Transport: Hemoglobin Dissociation Curve
11. Glucose Metabolism: Diabetes and Diagnostic Tests
12. · Laboratory Tests in Diabetes Mellitus
13. · Non-Enzymatic Glycation and HbA1c: Biochemical Foundation
14. · Polyol and Sorbitol Pathway: Mechanism of Chronic Complications
15. Hemoglobinopathies, Anemias and Porphyrias
16. · Structure and Synthesis of Hemoglobin
17. · Sickle Cell Anemia (Sickle Cell Disease)
18. · Thalassemias
19. · Porphyrias: Errors in Heme Synthesis
20. Plasma Lipids: Diagnosis and Cardiovascular Risk
21. · Lipid Profile and Its Limitations
22. · Lp(a): The Underestimated Risk Factor
23. Plasma Proteins: Electrophoresis and Clinical Interpretation
24. · Main Proteins and Their Clinical Meanings
25. · Serum Protein Electrophoresis (EPP) and Monoclonal Gammopathy
26. Vitamins and Coenzymes: Deficiencies with Clinical Relevance
27. Minerals, Metals and Mineral Metabolism Disorders
28. · Calcium, Phosphorus and Parathyroid Hormone
29. · Iron: Metabolism, Deficiency and Overload
30. · Copper: Wilson's Disease and Menkes Syndrome
31. Inborn Errors of Metabolism: Biochemical Diagnosis
32. · Aminoacidopathies
33. · Urea Cycle Disorders
34. Pharmacological Biochemistry: Molecular Mechanisms of Essential Drugs
35. · Antibiotics: Biochemical Targets
36. · Anticoagulants: Biochemical Foundation
37. · Immunomodulatory Drugs: Key Mechanisms
38. Tumor Markers: Biochemistry and Clinical Application
39. Purine and Pyrimidine Metabolism: Gout and Hyperuricemia
40. · De Novo synthesis vs. Purines Rescue Route
41. · Purine Catabolism and Uric Acid Production
42. · Gout: Biochemical Pathophysiology
43. · Synthesis and Degradation of Pyrimidines