Clinical Biochemistry: Pathophysiology and Diagnosis of Liver Diseases

Biochemistry · Basic Sciences

How it begins

Comprehensive and high-resolution analysis of the molecular pathophysiology, metabolic profiles, membrane enzymology, transporter genomics and markers of cytolysis and cholestasis in the central metabolic organ.

What it covers

1. Lobular Architecture and Hepatic Zoning
2. Liver Function and Enzymatic Kinetics Tests
3. · Aminotransferases (Transaminases): Indicators of Hepatocellular Injury
4. · Enzymes of Cholestasis and Canalicular Membrane Permeability
5. · Markers of Synthetic Function and Hepatic Reserve
6. Molecular Physiopathology of Cholestasis
7. · Pathophysiology of Cholestatic Pruritus and Malabsorption
8. Pathophysiology of Cytolysis and Necrosis
9. Autoimmune Liver Diseases
10. Fatty Liver Associated with Metabolic Dysfunction (MASLD / MASH)
11. Metal Overload Disorders
12. Virological Kinetics and Molecular Diagnostics
13. · Hepatitis B: Antigenic Complexity and Immunopathology
14. · Hepatitis C: Replication and Molecular Immunology
15. Severe Acute Liver Failure and Hyperammonemia
16. · Emergency Clinical and Predictive Markers
17. Fibrogenesis, Cirrhosis and Prognostic Scores
18. · Biochemical Prognostic Rating Systems
19. Inborn Errors of Liver Metabolism and Bilirubin
20. Biomarkers of Liver and Biliary Oncogenesis
21. Algorithmic Approaches in Laboratory Analysis
22. · Calculation of the R Factor for Liver Injury
23. Hepatic Physiopathological Integration