Epistemis

Surgery: Degenerative and Rheumatic Joint Pathology — Orthopedics and Traumatology

Surgery · Clinical Specialties

How it begins

Comprehensive scientific approach to osteoarthritis and inflammatory arthropathies. In-depth analysis of cartilage ultrastructure, cellular processes of the synovial pannus, biomechanical designs of implants and joint reconstruction protocols based on clinical evidence.

What it covers

  1. Joint Pathology
  2. Cartilage Biology
  3. · Macromolecular Composition of the Matrix
  4. · Histological Structure by Zones
  5. Etiopathogenesis of Osteoarthritis
  6. · Molecular Pathways of Matrix Degradation
  7. · Role of the Subchondral Bone and Structural Changes
  8. Pathophysiology of Rheumatic Arthropathies
  9. · The Normal Synovial Membrane vs. Rheumatoid Synovitis
  10. · Molecular Immunopathogenesis of Joint Destruction
  11. Clinical Manifestations and Natural History
  12. · Semiological Differentiation of Arthropathies
  13. · Kellgren and Lawrence Classification for Osteoarthritis
  14. Advanced Diagnostic Imaging
  15. · Conventional Loaded Radiology (Loaded)
  16. · Cartilage Mapping by Magnetic Resonance (MRI)
  17. · High Resolution Ultrasound and Nuclear Medicine
  18. Synovial Fluid and Biomarkers
  19. · Differential Diagnosis of Synovial Fluid
  20. · Biomarkers of Matrix Degradation and Turnover
  21. Total Hip Arthroplasty (THA)
  22. · Hip Biomechanics and Reconstruction
  23. · Tribology: Selection of Articulating Surfaces
  24. · Surgical Techniques and Approaches: Pros and Cons
  25. Total Knee Arthroplasty (TKA)
  26. · Mechanical Alignment vs. Kinematics
  27. · Gap Balancing Technique
  28. Shoulder and Small Extremities
  29. · Indications for Shoulder Arthroplasty
  30. · Small Extremity Arthroplasty (Hand and Foot)
  31. Redirection and Realignment Osteotomies
  32. · Valguizing Addition High Tibial Osteotomy (OTA)
  33. · Periacetabular Osteotomies (Ganz) and Hip Reorientation
  34. Surgical Cartilage Preservation Techniques
  35. · Algorithm for Choosing Repair Techniques
  36. Joint Arthrodesis
  37. · Modern Indications for Joint Fusion
  38. Prosthetic Joint Infection (Periprosthetic Infection)
  39. · Molecular Pathobiology of Biofilm
  40. · Diagnostic Criteria of the MSIS (Musculoskeletal Infection Society)
  41. · Surgical Algorithms and Rescue Options
  42. Aseptic Loosening and Reconstruction of Bone Defects
  43. · Biopathogenesis of Detritus-Induced Osteolysis
  44. · Paprosky Classification for Acetabular and Femoral Bone Defects
  45. Thromboembolic Prophylaxis and Post-Surgical Rehabilitation
  46. · Pathophysiology of Thrombotic Risk (Virchow Triad)
  47. · Pharmacological Scheme of Thromboprophylaxis
  48. · ERAS Protocol and Multimodal Rehabilitation

The complete study guide is in the app

This page summarizes the outline. The full interactive study guide —with high-yield diagrams, clinical tables, and board review cases— can be read inside Epistemis, completely offline and ad-free.

Subject
Surgery
Category
Clinical Specialties
Type
Study Guide
Sections
48
Reviewed
2026-08-02
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