Surgery: Bone and Soft Tissue Tumor Pathology — Oncological Reference

Surgery · Clinical Specialties

How it begins

Histopathological and radiological approach, oncological staging and complex therapeutic strategies for primary and metastatic bone neoplasms and soft tissue sarcomas of the extremity and axial skeleton.

What it covers

1. Bone and Soft Parts Tumor Pathology
2. General Principles and Epidemiology
3. · Epidemiological Magnitude and Distribution
4. · Concept of Anatomical Compartment and Tumor Microenvironment
5. · skip injuries
6. Diagnostic Evaluation and Imaging
7. · Clinical Presentation
8. · Conventional Radiology: The Initial Diagnostic Algorithm
9. · Patterns of Bone Destruction (Lodwick-Madewell Classification)
10. · Periosteal Reactions
11. · Magnetic Resonance (MRI) and Computed Tomography (CT)
12. Surgical Principles of Biopsy
13. · Biopsy Modalities
14. · Rigorous Surgical Technique in Incisional Biopsy
15. Classification Systems (Enneking and AJCC)
16. · Enneking Staging (MSTS) for Benign Bone Lesions
17. · Enneking Staging for Malignant Tumors (Bone and Soft Tissue Sarcomas)
18. · TNM Staging System (AJCC, 8th Edition) for Bone Sarcomas
19. Benign Bone Tumors and Pseudotumoral Lesions
20. · Bone-Forming Tumors (Osteogenic)
21. · Cartilage-Forming Tumors (Chondrogenic)
22. · Pseudotumor and Cystic Lesions
23. · Giant Cell Tumor of Bone (GCTB)
24. Primary Malignant Bone Tumors
25. · Osteosarcoma
26. · Ewing's sarcoma
27. · Chondrosarcoma
28. Soft Tissue Sarcomas (SPB)
29. · Key Histological Subtypes and Their Molecular Biology
30. · Pathways of Spread of Soft Tissue Sarcomas
31. Resection Margins and Anatomical Barriers
32. · Definitions of Surgical Margins according to Enneking
33. · The Concept of Natural Anatomical Barrier
34. Musculoskeletal Reconstruction Techniques
35. · Absolute Indications for Amputation in Sarcomas
36. · Biological Reconstruction Techniques
37. · Modular Massive Resection Endoprostheses (Megaprostheses)
38. · Van Nes Rotationplasty
39. Metastatic Bone Disease and Pathological Fractures
40. · Mechanism of Metastatic Bone Destruction (Vicious Circle)
41. · Evaluation of the Risk of Pathological Fracture: Mirels Scale
42. Systemic Therapies and Radiotherapy
43. · Targeted Therapy Drugs and Bone Modulators
44. · Indications for Radiotherapy in Musculoskeletal Pathology
45. Complications, Surveillance and Prognosis
46. · Specific Complications of Musculoskeletal Surgery
47. · Post-Treatment Surveillance Protocol for Sarcomas
48. · Survival Prognosis Stratification