Female Reproductive Endocrinology

Female Reproductive Endocrinology — Internal Medicine

How it begins

Comprehensive analysis of the hypothalamic-pituitary-ovarian axis, folliculogenesis, steroidogenesis, the menstrual cycle with its precise hormonal regulation, and the main clinical entities of female reproductive endocrinology

What it covers

1. Introduction and Conceptual Framework
2. Hypothalamus-Pituitary-Ovary Axis
3. · 1.1 Functional Anatomy of the Reproductive Hypothalamus
4. · 1.2 HPO Axis Feedback Mechanisms
5. GnRH — Gonadotropin Releasing Hormone
6. · 2.1 Structure and Synthesis
7. · 2.2 GnRH Pulsatility — The Pulse Generator
8. · 2.3 GnRH Receptor (GnRHR)
9. Gonadotropins: FSH and LH
10. · 3.1 Prolactin — Brief Reference in the Reproductive Context
11. Folliculogenesis
12. · 4.1 The Primordial Follicle Pool — The Ovarian Reserve
13. · 4.2 Stages of Follicular Development
14. Ovarian Steroidogenesis
15. · 5.1 The Two Cells, Two Gonadotropins Model
16. · 5.2 Ovarian Steroidogenesis Pathway
17. Normal Menstrual Cycle
18. · 6.1 Hormonal Changes Throughout the Cycle
19. · 6.2 Endometrial Cycle
20. Ovulation
21. Corpus Luteum
22. · 8.1 Formation and Luteinization
23. · 8.2 Progesterone Production
24. · 8.3 Luteolysis
25. · 8.4 Rescue of the Corpus Luteum by hCG
26. Ovarian Hormones — Systemic Actions
27. · 9.1 Estrogens
28. · 9.2 Progesterone
29. · 9.3 Inhibins, Activins, AMH and Follistatin
30. Female Puberty
31. · 10.1 Tanner Stages — Breast Development and Pubic Hair
32. · 10.2 Sequence of Pubertal Events
33. Menopause and Menopausal Transition
34. · 11.1 STRAW+10 Classification (Stages of Reproductive Aging Workshop)
35. · 11.2 Pathophysiology of Vasomotor Symptoms (Hot Flashes)
36. Endocrinology of Pregnancy
37. · 12.1 Human Chorionic Gonadotropin (hCG)
38. · 12.2 Fetoplacental Unit and Gestational Steroidogenesis
39. · 12.3 Placental Lactogen Hormone (hPL) and other pregnancy hormones
40. Breastfeeding Endocrinology
41. · 13.1 Hormonal Control of Lactogenesis
42. · 13.2 Oxytocin — Milk Ejection Reflex
43. · 13.3 Lactational Infertility (Lactational Amenorrhea)
44. Pathology of the Female Reproductive Axis
45. · 14.1 Polycystic Ovary Syndrome (PCOS)
46. · 14.2 Functional Hypothalamic Amenorrhea (FMA)
47. · 14.3 Premature Ovarian Insufficiency (POI) / Premature Ovarian Failure
48. · 14.4 Endometriosis — Endocrine Basis
49. · 14.5 Turner syndrome (45,X) — Endocrinology
50. · 14.6 Ovarian Hyperstimulation Syndrome (OHS)
51. · Integrating Principle