Epidemiology Applied to Communicable and Non-Communicable Diseases | Public Health Treaty

Public Health and Epidemiology · Clinical Bases

How it begins

A comprehensive and rigorous treatise on the forces of biological transmission and systemic determinants that govern the health of populations. From the compartmental predictive modeling of the reproductive reproduction number $R_0$ and the vector capacity of Macdonald, to the complex epigenetic interactions of the Barker hypothesis, the analytical biases of oncological screening and the techniques…

What it covers

1. Applied Epidemiology
2. Ecological Triad and Causality Networks in Complex Diseases
3. · 1.1 · Agent Attributes and Pathogenicity Dynamics
4. · 1.2 · Host Susceptibility and Genetic Factors
5. · 1.3 · The Environmental Component and Social Determinants of Health (DSS)
6. Mathematical Models of Transmission and Population Dynamics
7. · 2.1 · Mathematical Formulation of $R_0$ and the Effective Reproduction Number ($R_e$)
8. · 2.2 · SIR and SEIR Compartmental Models
9. · 2.3 · Herd Immunity Threshold (HIT)
10. Epidemiological Surveillance and Early Warning Systems
11. · 3.1 · Architecture of Surveillance Systems
12. · 3.2 · Syndromic Surveillance and Early Warning in the Digital Age
13. · 3.3 · Evaluation Attributes of a Surveillance System
14. Epidemiology Applied to Communicable Diseases I: Respiratory and Air Infections
15. · 4.1 · Tuberculosis (TB) and Antimicrobial Resistance Dynamics
16. · 4.2 · Molecular Epidemiology of Tuberculosis Transmission
17. Epidemiology Applied to Communicable Diseases II: Arbovirosis and Vector Transmission
18. · 5.1 · Macdonald Vector Capacity Formulation
19. · 5.2 · Immunological Pathophysiology of Dengue and Antibody Enhancement (ADE)
20. · 5.3 · Malaria Transmission Cycle
21. Epidemiology Applied to Communicable Diseases III: Sexually Transmitted Infections (STI) and Bloodborne Pathogens
22. · 6.1 · HIV-1 Transmission Dynamics and Viral Replication Control
23. · 6.2 · Viral Hepatitis B and C and Microelimination dynamics
24. · 6.3 · Syphilis and the Epidemiological Increase in Congenital Syphilis
25. Infections of Water and Food Origin and Emerging Zoonoses
26. · 7.1 · Cholera and the Molecular Pathophysiology of Water Transmission
27. · 7.2 · Human Rabies and the Pathophysiology of Retrograde Axonal Transport
28. Epidemiology of Non-Communicable Diseases (NCDs): Epidemiological Transition and Fetal Programming
29. · 8.1 · The Phases of Transition and Geographic Variability
30. · 8.2 · The Barker Hypothesis and the Developmental Origins of Health and Disease (DOHaD)
31. · 8.3 · Life Cycle Epidemiology Models
32. Cardiovascular Epidemiology, Obesity and Metabolic Syndrome
33. · 9.1 · Molecular Physiopathology of Atherosclerosis and Endothelial Dysfunction
34. · 9.2 · Epidemiology of Type 2 Diabetes Mellitus and Insulin Resistance
35. · 9.3 · The Framingham Heart Study
36. Epidemiological Oncology and Screening Biases
37. · 10.1 · Biological Carcinogens and Onco-Integration Mechanisms
38. · 10.2 · Screening Metrics and Biases in the Evaluation of Screening Programs
39. Epidemiology of Chronic Respiratory and Neurodegenerative Diseases
40. · 11.1 · Molecular Physiopathology of COPD and Protease-Antiprotease imbalance
41. · 11.2 · Alzheimer's Disease: The Amyloid Cascade and Tau Hyperphosphorylation
42. Epidemiological Research Designs and Bias Control
43. · 12.1 · Taxonomy and Structure of Epidemiological Designs
44. · 12.2 · Control of Selection and Information Biases
45. · 12.3 · Methods to Identify and Control Confusion
46. Applied Biostatistics and Survival Analysis
47. · 13.1 · Formulation of the Survival Function $S(t)$ and Hazard Function $h(t)$
48. · 13.2 · Kaplan-Meier Estimator and Log-Rank Test
49. · 13.3 · Cox Proportional Hazards Regression Model
50. Pharmacoepidemiology and Pharmacovigilance Systems
51. · 14.1 · Phase IV Clinical Trials and Postmarketing Pharmacovigilance
52. · 14.2 · RAM Imputability and Causality Algorithms
53. · 14.3 · Signal Detection Algorithms in Pharmacovigilance
54. Global Health, Global Burden of Disease and the "One Health" Approach
55. · 15.1 · Ecological Drivers of the Emergence of Zoonotic Diseases
56. · 15.2 · Integrated Disease Burden Metrics: DALYs / DALYs
57. · 15.3 · Key Principles in the Practice of Applied Epidemiology