Pharmacology of the Digestive System

Pharmacology of the Digestive System — Expert Level Guide

How it begins

Comprehensive analysis of the mechanisms of action, classification, pharmacokinetics, clinical correlations and rational use of pharmacological agents that modulate gastrointestinal, hepatic and pancreatic function.

What it covers

1. Digestive System
2. 1. Introduction and Physiological Bases
3. · 1.1 The Enteric Nervous System (ENS)
4. · 1.2 Neuroendocrine Control of Acid Secretion
5. · 1.3 Gastrointestinal Hormones of Pharmacological Relevance
6. 2. Pharmacology of Acid Secretion
7. · 2.1 Proton Pump Inhibitors (PPIs)
8. · 2.2 H2 Receptor Antagonists (Anti-H2)
9. · 2.3 Antacids
10. · 2.4 Prostaglandin Analogs — Misoprostol
11. 3. Helicobacter pylori — Pharmacology of Eradication
12. · 3.1 Antimicrobial Agents with Anti-H. Activity. pylori
13. · 3.2 Bismuth in Eradication
14. · 3.3 Eradication Regimes
15. 4. Pharmacology of GERD
16. · 4.1 Principles of Treatment
17. · 4.2 Baclofen in Refractory GERD
18. · 4.3 Alginate in Postprandial GERD
19. · 4.4 GERD in Pregnancy
20. 5. Gastropathy due to NSAIDs and Pharmacological Strategies
21. · 5.1 Pathophysiology of Gastric Damage due to NSAIDs
22. · 5.2 Gastrointestinal Risk Stratification
23. · 5.3 Selective COX-2 Inhibitors (Coxibs)
24. 6. Drugs That Modify Gastrointestinal Motility
25. · 6.1 Prokinetics
26. · 6.2 Antispasmodics
27. · 6.3 Sucralfate
28. 7. Laxatives and Constipation Treatment
29. · 7.1 Classification by Mechanism
30. 8. Antidiarrheal
31. · 8.1 Antiperistaltics Opioids
32. · 8.2 Bismuth Subsalicylate
33. · 8.3 Antisecretory: Racecadotril (Acetorphan)
34. · 8.4 Oral Rehydration Salts (ORS)
35. · 8.5 Treatment of Diarrhea due to C. difficile
36. 9. Irritable Bowel Syndrome — Pharmacology
37. · 9.1 Pharmacological Treatment by Subtype
38. 10. Inflammatory Bowel Disease (IBD)
39. · 10.1 Aminosalicylates (5-ASA)
40. · 10.2 Corticosteroids
41. · 10.3 Classic Immunomodulators
42. · 10.4 Biological Agents
43. 11. Liver Pharmacology
44. · 11.1 Chronic Hepatitis due to HBV
45. · 11.2 Chronic Hepatitis due to HCV
46. · 11.3 Liver Cirrhosis and its Complications
47. · 11.4 Autoimmune Hepatitis
48. · 11.5 NASH/MASH (Metabolic Steatohepatitis)
49. 12. Pancreatic Pharmacology
50. · 12.1 Exocrine Pancreatic Insufficiency (EPI)
51. · 12.2 Acute Pancreatitis
52. · 12.3 Chronic Pancreatitis — Pain
53. 13. Antiemetics
54. · 13.1 5-HT3 Antagonists (Setrons)
55. · 13.2 NK1 Antagonists (Substance P Antagonists)
56. · 13.3 Corticosteroids
57. · 13.4 Olanzapine
58. · 13.5 Other Antiemetics
59. 14. Probiotics, Prebiotics and Fecal Microbiota Transplantation
60. · 14.1 Probiotics
61. · 14.2 Fecal Microbiota Transplantation (FMT)
62. 15. Pharmacology of Obesity and Metabolic Disorders
63. · 15.1 GLP-1 Agonists (GLP-1 RA)
64. · 15.2 Orlistat
65. · 15.3 Other Drugs for Obesity
66. · 15.4 SGLT2 Inhibitors — GI and Metabolic Implications