Pharmacology of the Autonomic Nervous System

Pharmacology · Clinical Bases

How it begins

Comprehensive analysis of the receptors, neurotransmitters and drugs that modulate the sympathetic and parasympathetic nervous system, with precise molecular mechanisms, pharmacokinetics and clinical correlations of high therapeutic relevance.

What it covers

1. Organization of the Autonomic Nervous System
2. · General Architecture: Pre and Postganglionic Neurons
3. · Functional Comparison: Friendly vs. Parasympathetic
4. Autonomic Neurotransmission
5. · Synthesis, Storage, Release and Termination of Acetylcholine
6. · Synthesis, Storage, Release and Termination of Norepinephrine
7. Adrenergic Receptors: Types, Distribution and Signaling
8. · Alpha Adrenergic Receptors (α₁ and α₂)
9. · Beta Adrenergic Receptors (β₁, β₂, β₃)
10. · Dopaminergic Receptors in the ANS
11. Sympathomimetics: α and β agonists
12. · Endogenous and Clinical Catecholamines
13. · Selective β₂ Agonists — Bronchodilators
14. · α₁ Agonists — Vasoconstrictors and Decongestants
15. · Indirect and Mixed Sympathomimetics
16. · Central α₂ Agonists — Central Action Antihypertensives
17. Sympatholytics: α and β antagonists
18. · α Blockers (Alpha Blockers)
19. · Beta blockers (β-blockers, BB)
20. Cholinergic Receptors: Muscarinic and Nicotinic
21. · Muscarinic Receptors (M₁–M₅)
22. · Nicotinic Receptors (nAChR)
23. Cholinomimetics: Direct Muscarinic Agonists
24. Anticholinergics: Muscarinic Blockers
25. · Belladonna Alkaloids
26. · Antimuscarinics for Specific Clinical Use
27. Ganglionic Blockers
28. Neuromuscular Junction Drugs
29. Acetylcholinesterase Inhibitors (Anti-AChE)
30. Synthesis, Metabolism and Therapeutic Targets of Catecholamines
31. · Drugs that Interfere with Catecholamine Synthesis
32. · Drugs That Interfere with the Storage and Release of Catecholamines
33. · MAOIs and Dangerous Drug Interactions
34. Integration: Clinical Applications of the ANS
35. · Pharmacology of Glaucoma
36. · Pharmacology of Arterial Hypertension — Role of the ANS
37. · Pharmacology of Acute Heart Failure — The Use of Inotropes
38. · Sympathomimetic Toxidrome vs. cholinergic