Glomerulopathies: Nephrotic and Nephritic Syndromes | High Specialty Nephrology

Internal Medicine · Clinical Specialties

How it begins

An expert-level approach to the most complex entities in nephrology. From the molecular basis of the filtration barrier to the most recent KDIGO guidelines for the treatment of primary and secondary nephrotic and nephrotic glomerulopathies, including ultrastructural interpretation and high-resolution urine sediment analysis.

What it covers

1. Ultrastructural Anatomy of the Glomerular Filtration Barrier
2. Load and Size Selectivity in Glomerular Filtration
3. · 1. Size Selectivity
4. · 2. Charge Selectivity
5. Pathophysiology of Nephrotic Syndrome: Massive Proteinuria
6. · The Physiopathological Mechanism of Proteinuria
7. Metabolic and Clinical Consequences of Nephrotic Syndrome
8. · 1. Pathophysiology of Nephrotic Edema
9. · 2. Dyslipidemia, Hyperlipidemia and Lipiduria
10. · 3. Hypercoagulable State and Thromboembolic Risk
11. · 4. Extreme Susceptibility to Infections
12. Etiological Classification of Nephrotic Glomerulopathies
13. Minimal Change Disease (MCD)
14. · Etiology and Molecular Pathogenesis
15. · Histopathology Characteristic
16. · Treatment and Clinical Course
17. Focal and Segmental Glomerulosclerosis (FSGS)
18. · Etiology and Pathophysiological Classification
19. · Histopathology: Columbia Classification
20. · Treatment of Primary FSGS
21. Membranous Nephropathy (NM)
22. · Molecular Immunopathogenesis and Autoantibodies
23. · Ehrenreich and Churg stages by Electron Microscopy
24. · Treatment Based on KDIGO Risk Stratification
25. Membranoproliferative glomerulonephritis (MPGN)
26. · Complement-Based Pathophysiological Reclassification
27. · Immunopathology of C3 Glomerulopathy and C3 Nephritic Factor
28. · Histological Appearance by MO: The Membranoproliferative Pattern
29. Extreme Secondary Causes: Renal Amyloidosis and Diabetic Nephropathy
30. · 1. Renal Amyloidosis (AL/AA)
31. · 2. Diabetic Nephropathy (DN): The Metabolic and Hemodynamic Damage Model
32. Pathophysiology of Nephritic Syndrome: Inflammatory Glomerular Damage
33. · The Mechanism of Glomerular Inflammatory Damage
34. Poststreptococcal Glomerulonephritis (PEGN)
35. · Etiology and Immunopathogenesis
36. · Histological Findings and Immunofluorescence
37. · Clinical Course and Complement Profile
38. IgA nephropathy (Berger's disease)
39. · Immunopathogenesis: Four-Hit Hypothesis
40. · Oxford Histological Classification (MEST-C Score)
41. · Treatment of IgA Nephropathy
42. Rapidly Progressing Glomerulonephritis (RPGN)
43. · Pathophysiology of Crescent Formation
44. · Immunopathological Classification of PRGN
45. Pauciimmune Vasculitis Associated with ANCA
46. · Immunological Mechanisms of Neutrophil Activation
47. · ANCA Vasculitis Induction Treatment (PEXIVAS and ADVOCATE Trials)
48. Anti-Glomerular Basal Membrane Antibody Disease
49. · Goodpasture's Autoantigen
50. · Emergency Treatment
51. Lupus Nephritis: Immunopathology and Classification
52. · Immunological Pathophysiology of Lupus Nephritis
53. · ISN/RPS Histological Classification (2018 Revision)
54. · Updated Treatment of Proliferative Classes (III/IV)
55. Glomerular Thrombotic Microangiopathies (TMA)
56. · Pathophysiology of Glomerular Endothelial Damage
57. · Clinical and Etiological Subtypes
58. · Specific Treatment: C5 blockade with Eculizumab
59. Precision Analysis of Urinary Sediment
60. · Sediment Differentiation: Nephrotic Pattern vs. Nephritic Pattern
61. Precision Renal Biopsy and Decision Algorithms KDIGO
62. · Integrated Anatomopathological Processing and Analysis
63. · Therapeutic Decision Algorithm in Glomerulopathies (KDIGO 2021)