Glomerular Pathology · Internal Medicine

Internal Medicine · Clinical Specialties

How it begins

Expert compendium of diseases of the renal glomerulus: molecular pathophysiology, histological classification, clinical syndromes, primary and secondary etiologies, integrated diagnosis and updated therapeutic principles.

What it covers

1. Introduction and Classification of Glomerular Diseases
2. Functional Anatomy of the Glomerulus and Pathophysiology
3. · The Glomerular Filtration Barrier
4. · Mesangial Cells and Mesangial Matrix
5. · General Mechanisms of Glomerular Injury
6. Clinical Glomerular Syndromes
7. · Nephrotic Syndrome
8. · Nephritic Syndrome
9. · Rapidly Progressive Glomerulonephritis (RPGN)
10. · Asymptomatic Proteinuria / Asymptomatic Glomerular Hematuria
11. Minimal Change Disease (MCD)
12. · Epidemiology and Etiology
13. · Pathogenesis
14. · Histopathology
15. · Clinical Course and Response to Treatment
16. Focal and Segmental Glomerulosclerosis (FSGS)
17. · Columbia Concept and Classification
18. · Etiologies
19. · Histopathology
20. · Treatment and Prognosis
21. Membranous Glomerulonephritis (GNM)
22. · Pathogenesis: The Anti-PLA2R Antibody Paradigm
23. · Secondary Etiologies
24. · Histopathology
25. · Natural History and Rule of Thirds
26. · Treatment: Ponticelli and Rituximab Scheme
27. Membranoproliferative glomerulonephritis (MPGN)
28. IgA nephropathy (Berger's disease)
29. · Epidemiology and Pathogenesis: The "4 Hits" Model
30. · Clinical Presentation
31. · Histopathology: Oxford Classification (MEST-C)
32. · Treatment of IgA Nephropathy
33. Acute Diffuse Endocapillary Glomerulonephritis (Post-Infectious)
34. · Etiopathogenesis
35. · Histopathology
36. Rapidly Progressive Glomerulonephritis (RPGN)
37. · Crescents: Formation and Types
38. · RPGN treatment
39. Lupus Nephritis
40. · ISN/RPS Classification 2003 (Revised 2018)
41. · The "Full House" Pattern in Immunofluorescence
42. · Activity and Chronification Indices (NIH)
43. · Treatment of Proliferative Lupus Nephritis (Classes III/IV)
44. Diabetic Nephropathy
45. · Epidemiology and Pathophysiology
46. · Mogensen Stages (T1DM)
47. · The Kimmelstiel-Wilson Injury
48. · Nephroprotective Treatment
49. Renal Amyloidosis
50. · Clinical and Diagnostic Characteristics
51. ANCA vasculitis and Pauci-immune GN
52. · Classification of ANCA Vasculitis
53. · Pathogenesis of Glomerular Injury due to ANCA
54. · Histopathology
55. Goodpasture syndrome (Anti-GBM)
56. · Histopathology and Diagnosis
57. HIV Nephropathy and Other Glomerulopathies
58. · Alport syndrome
59. · Thin Basement Membrane Disease
60. · HBV nephropathy
61. Biochemical and Immunological Diagnosis of Glomerulopathies
62. · Uroanalysis and Urinary Sediment
63. · Quantification of Proteinuria
64. · Immunological Panel in Suspected Glomerulopathy
65. · Kidney Function and CKD Staging
66. · Image: Ultrasonography and Biopsy
67. Kidney Biopsy: Technique, Indications and Processing
68. · Indications and Contraindications
69. · Technique
70. Therapeutic Principles in Glomerulopathies
71. · Universal Nephroprotective Measures
72. · Immunosuppressants in Glomerulopathies: Mechanisms and Toxicity
73. · Management of Edema in Nephrotic Syndrome
74. Integrated Diagnostic Algorithms
75. · Algorithm: Adult Nephrotic Syndrome
76. · Algorithm: RPGN / Severe Acute Nephritic Syndrome