Epistemis

Gastrointestinal Bleeding — Expert Level Emergency Reference

Emergency · Clinical Specialties

How it begins

Expert-level clinical approach for diagnosis, hemodynamic resuscitation, endoscopic, pharmacological and endovascular therapy of upper and lower gastrointestinal bleeding in the emergency setting.

What it covers

  1. Definitions, classification and epidemiology of gastrointestinal bleeding
  2. · Epidemiology and Global Burden of Disease
  3. · Emerging Risk Factors and Vulnerable Populations
  4. Pathophysiology of hypovolemic shock and the systemic response
  5. · Hemodynamic and Neurohumoral Compensation Mechanisms
  6. · Pathophysiology at the Cellular Level, Ischemia and Lactic Acidosis
  7. · The Triad of Death in Hemorrhagic Shock
  8. Etiology of non-varicose upper gastrointestinal bleeding
  9. · Peptic Ulcer Disease (PUD)
  10. · Mucous Erosions and Stress Injuries
  11. · Mallory-Weiss syndrome
  12. · Dieulafoy injury
  13. · Other Vascular and Neoplastic Causes
  14. Etiology of varicose upper gastrointestinal bleeding
  15. · Pathophysiology of Portal Hypertension and Varicose Vein Formation
  16. · Varicose Rupture Factors
  17. · Salin Classification for Gastric Varicose Veins
  18. Etiology of lower gastrointestinal bleeding
  19. · Diverticular Colon Disease
  20. · Angiodysplasias (Vascular Ectasias)
  21. · Ischemic Colitis
  22. · Inflammatory Bowel Disease (IBD) and Anorectal Pathology
  23. Initial evaluation, triage and hemodynamic stabilization in the emergency room
  24. · Systematic Hemodynamic Evaluation
  25. · Airway Securement (ABCDE of Resuscitation)
  26. · Fluid Resuscitation and Hemodynamic Objectives
  27. · Transfusion Strategy: Restrictive versus Liberal
  28. · Correction of Coagulopathy
  29. Risk stratification scales
  30. · Glasgow-Blatchford Score (GBS)
  31. · Rockall Scale
  32. · AIMS65
  33. · Oakland Score for Low Gastrointestinal Bleeding
  34. Diagnostic and therapeutic approach to non-varicose upper gastrointestinal bleeding
  35. · Acid Suppressive Pharmacological Therapy with PPI
  36. · Appropriate Timing of Endoscopy (Timing)
  37. · Use of Prokinetics: Erythromycin and Metoclopramide
  38. · Endoscopic Hemostasis Techniques
  39. · Refractory Management: Angioembolization and Surgical
  40. Specific approach to varicose upper gastrointestinal bleeding
  41. · Early Vasoactive Therapy
  42. · Prophylactic Antibiotic Therapy
  43. · Endoscopic Therapeutics: Band Ligation versus Tissue Adhesives
  44. · Emergency Rescue Strategies
  45. Diagnostic and therapeutic approach to lower gastrointestinal bleeding
  46. · Emergency versus Elective Colonoscopy
  47. · Stratification of Diagnostic Imaging Tests: CT Angio
  48. · Superselective Rescue Angiography and Embolization
  49. · Emergency Surgical Indications: Segmental Colectomy versus Subtotal
  50. Gastrointestinal bleeding from the middle intestine (obscure origin)
  51. · Definition and Change of Nomenclature
  52. · Etiology of Midgut Bleeding
  53. · Middle Intestine Diagnostic Testing Algorithm
  54. Perioperative management of anticoagulated and antiplatelet patients
  55. · Anticoagulation Reversal Protocols
  56. · Management and Suspension of Antiplatelet Therapy
  57. · Criteria for Safe Restart of Anticoagulation
  58. Systemic complications, monitoring and intensive care
  59. · Prerenal Acute Renal Failure (AKI) and Acute Tubular Necrosis (ATN)
  60. · Myocardial Ischemia Type 2 (Secondary Myocardial Infarction)
  61. · Hepatic Encephalopathy in Varicose Hemorrhage
  62. Detailed emergency pharmacological protocols
  63. Integrated decision-making algorithms and on-call checklist
  64. · Decision Making Algorithm in Upper Gastrointestinal Bleeding (UGIB)
  65. · Decision Making Algorithm in Lower Gastrointestinal Bleeding (LGIB)
  66. · Safety and Quality of Care Checklist for the Emergency Department

The complete study guide is in the app

This page summarizes the outline. The full interactive study guide —with high-yield diagrams, clinical tables, and board review cases— can be read inside Epistemis, completely offline and ad-free.

Subject
Emergency
Category
Clinical Specialties
Type
Study Guide
Sections
66
Reviewed
2026-09-05
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