Epistemis

Clinical Perioperative Management — Medicine and Surgery

Surgery · Clinical Specialties

How it begins

Multimodal risk assessment, physiological optimization of organ systems, control of antithrombotic therapy and accelerated recovery protocols based on contemporary clinical evidence and international guidelines.

What it covers

  1. Surgery: Perioperative Management
  2. Global Surgical Risk Assessment
  3. · Stratification of Physical Condition: American Society of Anesthesiologists (ASA) Scale
  4. · Revised Cardiac Risk Index (RCRI or Lee Index)
  5. · Evaluation of Functional Capacity and Metabolic Equivalents (METs)
  6. · Multivariate Predictive Tools: NSQIP MICA Calculator
  7. Physiological Response to Surgical Stress
  8. · Afferent and Neuroendocrine Signaling Cascade
  9. · Metabolic Response: Cuthbertson Phases
  10. · The Immunological and Inflammatory Cascade
  11. Evaluation and Cardiovascular Risk
  12. · Evaluation Algorithm in Non-Cardiac Surgery (ESC/ESAIC Guidelines 2022)
  13. · Classification of Procedures According to Intrinsic Cardiovascular Risk
  14. · Indications for Preoperative Diagnostic Tests
  15. · The Role of Cardiac Biomarkers: NT-proBNP and hs-cTn
  16. Perioperative Cardiovascular Pharmacotherapy
  17. · The Beta-Blocker Controversy: Lessons from the POISE-1 Trial
  18. · ACEI and ARB: Continue or Suspend?
  19. · Management of Statins and Diuretics
  20. Management of Antithrombotic Therapy
  21. · Double Antiplatelet Aggregation (DAPT) in Patients with Coronary Stents
  22. · Management of Direct Acting Oral Anticoagulants (DOACs) and Vitamin K Antagonists
  23. · Bridging Therapy: Indications after the BRIDGE Trial
  24. Pulmonary Risk and Management
  25. · Postoperative Pulmonary Complications (PPC)
  26. · Pulmonary Risk Stratification: ARISCAT Scale
  27. · Pathophysiology of Atelectasis and Diaphragmatic Dysfunction
  28. · Pulmonary Prevention and Optimization Strategies
  29. · Obstructive Sleep Apnea (OSA): STOP-BANG Screening Questionnaire
  30. Kidney Function and Perioperative Hydration
  31. · Postoperative Acute Kidney Injury (AKI)
  32. · Perioperative Fluid Therapy: Liberal vs. Restrictive (RELIEF Trial)
  33. · Goal Guided Fluid Therapy (GDTP / GDFT)
  34. · Perioperative Sodium Disorders: Acute Hyponatremia
  35. Glycemic Control and Endocrine Disorders
  36. · Perioperative Glycemic Control: Lessons from the NICE-SUGAR Trial
  37. · Management of Oral and Non-Insulin Antidiabetics
  38. · Secondary Adrenal Insufficiency and Stress Steroid Therapy
  39. Antimicrobial Prophylaxis and Infection Control
  40. · Antibiotic Administration and Selection Criteria
  41. · The 60 Minute Rule and Redosing Criteria
  42. · Regimes of Choice according to Surgical Location
  43. Hemostatic Management and Perioperative Transfusion
  44. · Transfusion Strategy: Restrictive vs. Liberal (TRICS III Test)
  45. · Viscoelastic Coagulation Tests: TEG and ROTEM
  46. · Use of Perioperative Antifibrinolytics: POISE-3 Trial
  47. Management of the Elderly and Frail Patient
  48. · Frailty as an Independent Predictor of Complications
  49. · Postoperative Delirium (POD) vs. Postoperative Cognitive Dysfunction (POCD)
  50. · Non-Pharmacological Delirium Prevention Strategies (HELP Protocol)
  51. · Polypharmacy and Inappropriate Prescription: Beers Criteria
  52. ERAS / Fast-Track protocols
  53. · Components of a Multimodal ERAS Protocol
  54. Multimodal Analgesia and Pain Control
  55. · The Multimodal Analgesia Paradigm
  56. · Adverse Effects of Indiscriminate Use of Opioids
  57. · Prevention and Management of Postoperative Nausea and Vomiting (PONV)
  58. Major Postoperative Complications
  59. · Postoperative Fever: The Diagnostic Rule of the "5 Ws"
  60. · Venous Thromboembolism Prophylaxis: Caprini Scale
  61. · Postoperative Paralytic Ileus and Anastomosis Dehiscence

The complete study guide is in the app

This page summarizes the outline. The full interactive study guide —with high-yield diagrams, clinical tables, and board review cases— can be read inside Epistemis, completely offline and ad-free.

Subject
Surgery
Category
Clinical Specialties
Type
Study Guide
Sections
61
Reviewed
2026-08-02
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