Epistemis

Surgery: Research and Technological Advances — Cutting-edge Medicine and Surgery

Surgery · Clinical Specialties

How it begins

An exhaustive, methodological and interdisciplinary compendium on the mechanical, digital, bioengineering and molecular advances that redefine modern surgical praxis and perioperative medicine.

What it covers

  1. Advances and New Surgical Frontiers
  2. Surgical Research Methodology
  3. · The IDEAL Methodological Framework
  4. · The Placebo Paradox (Sham Surgery) in Research
  5. · CUSUM Analysis for Quality Control
  6. Pathophysiology of Minimal Invasion
  7. · Insufflation and Systemic Physiology
  8. · The Inflammatory and Acute Phase Cascade
  9. · Splanchnic Microcirculation and Ischemia-Reperfusion
  10. Robotic and Kinematic Surgery
  11. · The Kinematics of the Robotic Arm
  12. · Degrees of Freedom and End Effectors (EndoWrist)
  13. · Partial Autonomy: The STAR Project
  14. Artificial Intelligence, Computer Vision and Machine Learning
  15. · Computer Vision in the Smart Operating Room
  16. · Classification of Surgical Events in Real Time (Surgical Process Models)
  17. · Clinical Data Integration and Preoperative Prediction
  18. Immersive Realities and Surgical Navigation
  19. · Holographic Planning and Three-Dimensional Reconstruction
  20. · Stereotaxic Navigation Systems
  21. · Tissue Deformation Compensation ("Brain Shift" and "Tissue Drift")
  22. Fluorescence Guided Surgery
  23. · Physiology and Optical Properties of Indocyanine Green (ICG)
  24. · Clinical Applications of Fluorescence Imaging with ICG
  25. · Targeted Selective Fluorescence Agents (Targeted Molecular Imaging)
  26. 3D Printing, Biopressure and Allotransplantation of Vascularized Composite Tissues (VCA)
  27. · Patient Specific Osteotomy Guidelines (PSI)
  28. · 3D Biopressure: Functional Tissue Structures
  29. · Allogeneic Vascularized Composite Tissue Transplantation (VCA)
  30. Precision Therapies in Surgical Oncology
  31. · HIPEC: Hyperthermic Intraperitoneal Chemotherapy
  32. · PIPAC: Pressurized Intraperitoneal Aerosol Chemotherapy
  33. · Comparative Efficacy of Intraperitoneal Therapies
  34. Biomaterials, Bioengineering and Nanosurgery
  35. · Active Hemostatic Agents and Biological Sealants
  36. · Decellularized Extracellular Matrices (dECM)
  37. · Nanotechnology and Precision Surgery (Nanosurgery)
  38. Genetic Editing and Xenotransplantation
  39. · CRISPR-Cas9 as a Technological Enabler for Xenotransplantation
  40. · The Pathophysiology of Xenograft Rejection
  41. Telesurgery and Global Connectivity
  42. · Physics of Latency and Limits of Psychomotor Skills
  43. · Advanced Network Architecture: Slicing Networks and Edge Computing
  44. · Clinical Milestones: From Operation Lindbergh to Space Surgery
  45. Ergonomics, Human Factors and the Surgical Black Box
  46. · Comparative Physical Ergonomics of the Surgeon
  47. · The Surgical Black Box
  48. Precision Anesthesiology and Pathophysiological ERAS Protocol
  49. · The ERAS Paradigm (Enhanced Recovery After Surgery)
  50. · Goal Guided Water Therapy (GDFT)
  51. · Anesthetic Depth Monitoring for the Prevention of Delirium
  52. Clinical Borders, Ethical Aspects and Regulation
  53. · Robotic Autonomy and the Dilemma of Legal Responsibility
  54. · Validation and Regulatory Approval (FDA and CE Marking)
  55. · Equity and Distribution in Global Surgery

The complete study guide is in the app

This page summarizes the outline. The full interactive study guide —with high-yield diagrams, clinical tables, and board review cases— can be read inside Epistemis, completely offline and ad-free.

Subject
Surgery
Category
Clinical Specialties
Type
Study Guide
Sections
55
Reviewed
2026-08-02
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