Epistemis

Pain Medicine: Evaluation, Diagnosis and Clinical History

Pain Medicine · Clinical Specialties

How it begins

A comprehensive and systematic treatise on the neurobiology of nociception, the methodology of multidimensional anamnesis, the semiology of acute and chronic pain syndromes, and precision clinical and paraclinical diagnostic tools in contemporary algorithmic medicine.

What it covers

  1. Neurobiology and Pathophysiology of Pain
  2. · 1.1 Transduction and Nociceptive Receptors
  3. · 1.2 Transmission and Spinal Pathways
  4. · 1.3 Modulation and Descending Paths
  5. · 1.4 Pain Processing and Corticalization
  6. · 1.5 Pathophysiology of Central Sensitization
  7. Systematic Classification of Pain
  8. · 2.1 Temporal Taxonomy: Acute Pain vs. Chronic Pain
  9. · 2.2 Pathophysiological Classification
  10. · 2.3 Topographic Classification and Spatial Distribution
  11. · 2.4 International Classification of Diseases (ICD-11) and Chronic Pain
  12. The Clinical History of the Patient with Pain
  13. · 3.1 Systematic Semiotics of Pain: The Acronym ALICIA-DR
  14. · 3.2 Temporal Profile and Longitudinal Evolution
  15. · 3.3 Personal History, Comorbidities and Family History
  16. · 3.4 Risk Stratification and Substance Use Assessment
  17. Warning Flags in Pain Assessment
  18. · 4.1 Red Flags: Indicators of Serious Organic Pathology
  19. · 4.2 Yellow Flags: Psychosocial and Cognitive Factors
  20. · 4.3 Blue and Black Flags: Labor and Institutional Factors
  21. · 4.4 Orange Flags: Serious Psychopathology
  22. Multidimensional Evaluation and Measurement Instruments
  23. · 5.1 Unidimensional Intensity Scales
  24. · 5.2 Multidimensional Scales
  25. · 5.3 Neuropathic Pain Screening Tools
  26. · 5.4 Measurement of Impact on Quality of Life and Functionality
  27. Physical and Myofascial Examination of the Patient with Pain
  28. · 6.1 Static and Dynamic Inspection
  29. · 6.2 Palpation and Myofascial Examination
  30. · 6.3 Joint examination and Sacroiliac Tests
  31. · 6.4 Cervical and Lumbar Spinal Provocation Maneuvers
  32. Precision Sensitive Neurological Examination
  33. · 7.1 Examination of Thick Myelinated Fibers (Aβ Fibers)
  34. · 7.2 Examination of Fine Fibers (Aδ Fibers and C Fibers)
  35. · 7.3 Evaluation of Allodynia and Hyperalgesia
  36. · 7.4 Somatotopy and Dermatomas of Clinical Relevance
  37. Differential Diagnosis of Major Chronic Pain Syndromes
  38. · 8.1 Complex Regional Pain Syndrome (CRPS)
  39. · 8.2 Myofascial Pain Syndrome versus Fibromyalgia
  40. · 8.3 Fibromyalgia and Nociplastic States
  41. · 8.4 Peripheral Neuropathies and Compressive Radiculopathies
  42. Complementary Tests and Precision Diagnosis
  43. · 9.1 Structural and Functional Neuroimaging
  44. · 9.2 Clinical Neurophysiology Studies
  45. · 9.3 Quantitative Sensory Testing (QST - Quantitative Sensory Testing)
  46. · 9.4 Precision Diagnostic and Interventional Blocks
  47. Evaluation of Pain in Special Populations
  48. · 10.1 Pediatric Patient
  49. · 10.2 Geriatric Patient and Dementia
  50. · 10.3 Critical and Non-Communicative Patient in the ICU
  51. Diagnostic Algorithm and Guide for the Clinical Report
  52. · 11.1 Standard Structure of the Pain Medicine Report
  53. · 11.2 Integrated Multidimensional Diagnosis

The complete study guide is in the app

This page summarizes the outline. The full interactive study guide —with high-yield diagrams, clinical tables, and board review cases— can be read inside Epistemis, completely offline and ad-free.

Subject
Pain Medicine
Category
Clinical Specialties
Type
Study Guide
Sections
53
Reviewed
2026-08-02
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