Pain Medicine: Evaluation, Diagnosis and Clinical History
Pain Medicine · Clinical Specialties
How it begins
A comprehensive and systematic treatise on the neurobiology of nociception, the methodology of multidimensional anamnesis, the semiology of acute and chronic pain syndromes, and precision clinical and paraclinical diagnostic tools in contemporary algorithmic medicine.
What it covers
- Neurobiology and Pathophysiology of Pain
- · 1.1 Transduction and Nociceptive Receptors
- · 1.2 Transmission and Spinal Pathways
- · 1.3 Modulation and Descending Paths
- · 1.4 Pain Processing and Corticalization
- · 1.5 Pathophysiology of Central Sensitization
- Systematic Classification of Pain
- · 2.1 Temporal Taxonomy: Acute Pain vs. Chronic Pain
- · 2.2 Pathophysiological Classification
- · 2.3 Topographic Classification and Spatial Distribution
- · 2.4 International Classification of Diseases (ICD-11) and Chronic Pain
- The Clinical History of the Patient with Pain
- · 3.1 Systematic Semiotics of Pain: The Acronym ALICIA-DR
- · 3.2 Temporal Profile and Longitudinal Evolution
- · 3.3 Personal History, Comorbidities and Family History
- · 3.4 Risk Stratification and Substance Use Assessment
- Warning Flags in Pain Assessment
- · 4.1 Red Flags: Indicators of Serious Organic Pathology
- · 4.2 Yellow Flags: Psychosocial and Cognitive Factors
- · 4.3 Blue and Black Flags: Labor and Institutional Factors
- · 4.4 Orange Flags: Serious Psychopathology
- Multidimensional Evaluation and Measurement Instruments
- · 5.1 Unidimensional Intensity Scales
- · 5.2 Multidimensional Scales
- · 5.3 Neuropathic Pain Screening Tools
- · 5.4 Measurement of Impact on Quality of Life and Functionality
- Physical and Myofascial Examination of the Patient with Pain
- · 6.1 Static and Dynamic Inspection
- · 6.2 Palpation and Myofascial Examination
- · 6.3 Joint examination and Sacroiliac Tests
- · 6.4 Cervical and Lumbar Spinal Provocation Maneuvers
- Precision Sensitive Neurological Examination
- · 7.1 Examination of Thick Myelinated Fibers (Aβ Fibers)
- · 7.2 Examination of Fine Fibers (Aδ Fibers and C Fibers)
- · 7.3 Evaluation of Allodynia and Hyperalgesia
- · 7.4 Somatotopy and Dermatomas of Clinical Relevance
- Differential Diagnosis of Major Chronic Pain Syndromes
- · 8.1 Complex Regional Pain Syndrome (CRPS)
- · 8.2 Myofascial Pain Syndrome versus Fibromyalgia
- · 8.3 Fibromyalgia and Nociplastic States
- · 8.4 Peripheral Neuropathies and Compressive Radiculopathies
- Complementary Tests and Precision Diagnosis
- · 9.1 Structural and Functional Neuroimaging
- · 9.2 Clinical Neurophysiology Studies
- · 9.3 Quantitative Sensory Testing (QST - Quantitative Sensory Testing)
- · 9.4 Precision Diagnostic and Interventional Blocks
- Evaluation of Pain in Special Populations
- · 10.1 Pediatric Patient
- · 10.2 Geriatric Patient and Dementia
- · 10.3 Critical and Non-Communicative Patient in the ICU
- Diagnostic Algorithm and Guide for the Clinical Report
- · 11.1 Standard Structure of the Pain Medicine Report
- · 11.2 Integrated Multidimensional Diagnosis
The complete study guide is in the app
This page summarizes the outline. The full interactive study guide —with high-yield diagrams, clinical tables, and board review cases— can be read inside Epistemis, completely offline and ad-free.
- Subject
- Pain Medicine
- Category
- Clinical Specialties
- Type
- Study Guide
- Sections
- 53
- Reviewed
- 2026-08-02