Epistemis

Mineral and Bone Metabolism

Mineral and Bone Metabolism | Internal medicine

How it begins

Expert and comprehensive reference on the physiology of calcium, phosphorus, magnesium and vitamin D; laboratory and imaging diagnostic methods including densitometry and remodeling biomarkers; and the clinical diagnosis of the main syndromes: hypercalcemia, osteoporosis, osteomalacia, hyperparathyroidism, BMT-CKD and neoplasms with bone impact. Based on KDIGO 2017, NOF 2023, AACE/ACE 2020 and…

What it covers

  1. Calcium and Phosphorus Homeostasis
  2. Parathyroid Hormone (PTH): Synthesis, Secretion and Actions
  3. Vitamin D, FGF-23, Klotho and Calcitonin
  4. Cellular Biology of Bone Remodeling
  5. Serum Calcium: Total, Ionized and Albumin Correction
  6. Phosphorus, Magnesium and PTH: Integrated Interpretation
  7. Vitamin D: 25-OHD and 1,25(OH)₂D — Measurement and Interpretation
  8. Biochemical Markers of Bone Remodeling
  9. Bone Densitometry (DXA) and FRAX Tool
  10. Diagnosis by Imaging in Mineral and Bone Pathology
  11. Hypercalcemia: Differential Diagnosis and Management
  12. Primary Hyperparathyroidism: Diagnosis, Location and Treatment
  13. Hypocalcemia, Hypoparathyroidism and Pseudohypoparathyroidism
  14. Rickets and Osteomalacia
  15. Phosphorus Disorders: Hypophosphatemia and Hyperphosphatemia
  16. Magnesium Disorders: Hypomagnesemia and Hypermagnesemia
  17. Osteoporosis: Diagnosis, Risk of Fracture and Treatment
  18. Paget's Disease of Bone and Other Osteodystrophies
  19. CKD-MBD and Neoplasms with Impact on Bone Metabolism
  20. Integrated Diagnostic Algorithms in Mineral-Bone Metabolism

The complete study guide is in the app

This page summarizes the outline. The full interactive study guide —with high-yield diagrams, clinical tables, and board review cases— can be read inside Epistemis, completely offline and ad-free.

Subject
Internal Medicine
Category
Clinical Specialties
Type
Study Guide
Sections
20
Reviewed
2026-08-02
Download Epistemis