Epistemis

Clinical Nutrition — Organ Failure and Critical Patient

Clinical Nutrition · Clinical Specialties

How it begins

A rigorous scientific study of metabolic reprogramming, mitochondrial thermodynamics and molecular nutritional support strategies in states of shock, multiple organ dysfunction and terminal parenchymal failure.

What it covers

  1. Organ Failure and Critical Patient
  2. Metabolic Phases of Acute Injury: Ebb, Flow and Recovery
  3. · The Dynamics of Injury: Chronological and Molecular Analysis
  4. · The Cytokine Storm and the Reprogramming of the Energy Substrate
  5. Evaluation of Nutritional Status in Critical Patients
  6. · Limitations of Classic Assessment Methods
  7. · GLIM (Global Leadership Initiative on Malnutrition) Diagnostic Criteria
  8. · Risk Stratification: NUTRIC Score
  9. · Indirect Calorimetry: The Gold Standard
  10. Energy Requirements, Macronutrients and Lipid Profiles
  11. · Hypocaloric Hyperproteic Strategy in the Acute Phase
  12. · Amino Acid Formulation and the Role of Nitrogen
  13. · Third Generation Lipid Emulsions
  14. Enteral Nutrition (EN): Physiology, Indications and Access
  15. · The Intestinal Barrier as an Immune Organ in Injury
  16. · Advanced Enteral Feeding Accesses
  17. Parenteral Nutrition (PN): Indications, Complications and Monitoring
  18. · Clear Indications for Parenteral Nutritional Support
  19. · Venous Access Routes and Osmolarity Calculation
  20. · Critical Clinical Complications of Parenteral Nutrition
  21. Refeeding Syndrome
  22. · Pathophysiology of Hydroelectrolyte Collapse
  23. · The Critical Role of Thiamine (Vitamin B1)
  24. Nutritional Support in Respiratory Failure and ARDS
  25. · Carbon Dioxide Overload: The Role of Carbohydrates
  26. · Acute Respiratory Distress Syndrome (ARDS): Volume and Lipid Restriction
  27. Nutritional Support in Acute Kidney Injury and Nephropathy
  28. · Metabolic Alterations of the Uremic State
  29. · Protein Adjustment: Conservative Management vs. Continuous Renal Replacement Therapies (CRRT)
  30. Nutritional Support in Liver Failure and Hyperammonemia
  31. · Pathophysiology of Liver Dysfunction in Critical Care
  32. · The Amino Acid Hypothesis and the Fischer Quotient
  33. Nutritional Support in Heart Failure and Cardiac Cachexia
  34. · Metabolic Reprogramming of the Ischemic Cardiomyocyte
  35. · Pathophysiology of Cardiac Cachexia
  36. · Principles of Nutritional Support in Critical Heart Failure
  37. Nutritional Support in Sepsis and Septic Shock
  38. · Cytopathic Hypoxia and Septic Mitochondrial Dysfunction
  39. · The Dilemma of Early Enteral Nutrition in Vasodependence
  40. Nutritional Support in Severe Acute Pancreatitis (PAG)
  41. · The Paradigm Revolution: The End of Pancreatic Rest
  42. · Access Route: Gastric Tube or Jejunal Tube?
  43. · Recommended Formulation in PAG
  44. Nutritional Management in High Output Enterocutaneous Fistulas
  45. · Pathophysiology of Hydroelectrolyte and Nutritional Imbalance
  46. · Reconstructive Strategies and the Fistuloclysis Technique
  47. Immunonutrition, Pharmaconutrition and Tolerance Monitoring
  48. · Specific Pharmaconutritional Substrates
  49. · Biomarkers of Tolerance and Enterocyte Mass

The complete study guide is in the app

This page summarizes the outline. The full interactive study guide —with high-yield diagrams, clinical tables, and board review cases— can be read inside Epistemis, completely offline and ad-free.

Subject
Clinical Nutrition
Category
Clinical Specialties
Type
Study Guide
Sections
49
Reviewed
2026-08-02
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